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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Research Methodology & Design Research

Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.

Showing 91-100 of 702 results

Spinal Cord InjurySurgeryResearch Methodology & Design

Ultra-early ( ≤ 8 hours) surgery for thoracolumbar spinal cord injuries: A systematic review and meta-analysis

North American Spine Society Journal (NASSJ), 2023 • October 5, 2023

This systematic review and meta-analysis examined the impact of ultra-early (≤ 8 hours) surgical decompression on neurological recovery in patients with thoracolumbar spinal cord injuries (tSCI). The ...

KEY FINDING: Patients undergoing decompression within 8 hours of tSCI showed a significant improvement in the mean AIS score.

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NeuroimagingResearch Methodology & Design

Harmonization of multi‑site diffusion tensor imaging data for cervical and thoracic spinal cord at 1.5 T and 3 T using longitudinal ComBat

Scientific Reports, 2023 • November 1, 2023

This study examines the variability of DTI of the spinal cord between MR scanners of differing field strengths, hardware capabilities, and manufacturers by scanning a sample of thirty healthy adult su...

KEY FINDING: Large variability was found in diffusivity measures across different scanners, particularly in the upper thoracic region.

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Spinal Cord InjuryCritical CareResearch Methodology & Design

Guidelines for neuroprognostication in adults with traumatic spinal cord injury

Neurocrit Care, 2024 • November 13, 2023

These guidelines provide recommendations about the reliability of acute-phase predictors of mortality, functional outcome, American Spinal Injury Association Impairment Scale grade conversion, and rec...

KEY FINDING: Pathologic findings on magnetic resonance imaging (MRI), neurological level of injury, and severity of injury are moderately reliable predictors of American Spinal Cord Injury Impairment Scale (AIS) improvement.

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Spinal Cord InjuryTraumaResearch Methodology & Design

Post-discharge follow-up of patients with spine trauma in the National Spinal Cord Injury Registry of Iran during the COVID-19 pandemic: Challenges and lessons learned

Chinese Journal of Traumatology, 2024 • November 10, 2023

This study evaluated the ability of the National Spinal Cord Injury Registry of Iran (NSCIR-IR) to assess the quality of care (QoC) for spine trauma patients through post-discharge follow-up during th...

KEY FINDING: The success rate of follow-ups by telephone was 73.38% and 67.05% for non-SCI patients, while face-to-face follow-ups for SCI patients had a success rate of 66.67%.

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SurgerySpinal DisordersResearch Methodology & Design

Surgical tool entrapment in a young patient with recurrent lumbar spinal stenosis: a case report

Clin Case Rep, 2023 • November 4, 2023

This case report describes a 24-year-old male with lumbar spinal stenosis (LSS) who experienced recurrent pain after spinal fusion due to a retained surgical curette edge. The patient underwent multip...

KEY FINDING: Surgical tool entrapment can occur during spinal fusion procedures, even though it is rare.

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NeurologySpinal DisordersResearch Methodology & Design

Cervical Spondylosis as a Potential Cause of Venous Hypertensive Myelopathy: A Case Report

Am J Case Rep, 2023 • December 17, 2023

This case report presents an uncommon instance of cervical spondylotic myelopathy (CSM) with rapid neurological deterioration and unusual growth of the high-signal intensity area on T2-weighted MRI, e...

KEY FINDING: The patient's symptoms and MRI results improved significantly after surgical decompression, suggesting that cervical spondylosis can indeed cause VHM.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

Clinical Practice Guideline Development for Autonomic Dysreflexia in Spinal Cord Injury

Medical Journal of the Islamic Republic of Iran, 2023 • October 9, 2023

This study aimed to present Clinical Practice Guidelines (CPG) development for AD in SCI in different conditions. A national multidisciplinary panel of experts performed the decision-making step, whic...

KEY FINDING: After reviewing numerous articles, the expert panel adapted existing recommendations into a protocol for managing patients with autonomic dysreflexia.

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SurgerySpinal DisordersResearch Methodology & Design

Paralysis of the lower limbs caused by spontaneous spinal epidural hematoma: A case report

International Journal of Surgery Case Reports, 2024 • January 2, 2024

This case report describes the successful surgical management of a 76-year-old male with spontaneous spinal epidural hematoma (SSEH) who presented with sudden chest and back pain and paralysis of the ...

KEY FINDING: SSEH can present with sudden neck, back, or lumbar pain, often followed by motor and sensory disturbances and urinary dysfunction.

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NeurologyTraumaResearch Methodology & Design

Emergency Medical Services dispatcher recognition of stroke: A systematic review

European Stroke Journal, 2024 • May 1, 2024

This systematic review evaluated 24 papers on EMS dispatcher recognition of stroke, revealing significant variations in stroke recognition across different EMS settings. The review found a wide range ...

KEY FINDING: The sensitivity of stroke recognition by EMS dispatchers varied widely, ranging from 17.9% to 83.0% across the studies examined.

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Spinal Cord InjuryBioinformaticsResearch Methodology & Design

Studying missingness in spinal cord injury data: challenges and impact of data imputation

BMC Medical Research Methodology, 2024 • January 1, 2024

This study addresses the impact of missing data in SCI data sources on the results reported, focusing on the type of variable in which data is missing, the pattern in which the data is missing, and th...

KEY FINDING: Mean imputation can lead to results that strongly deviate from expected results.

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