Pulmonology Research

KEY FINDING: The primary hypothesis is that nocturnal CPAP will improve neuropsychological functioning more than usual care alone.

KEY FINDING: Forced vital capacity (FVC) significantly increased during the 3-week abdominal functional electrical stimulation (AFES) training program.

KEY FINDING: RMT has a statistically significant effect on vital capacity, maximal inspiratory pressure, and maximal expiratory pressure in individuals with cervical SCI.

KEY FINDING: FVC, FEV1, PImax, PEmax, amount of overall sEMG activity and rate of motor unit recruitment were significantly increased after LT (p<0.05)

KEY FINDING: Systemic delivery of PAP4 starting at 8 weeks after C2 hemisection promoted substantial, long-distance regeneration of injured bulbospinal rostral Ventral Respiratory Group (rVRG) axons.

KEY FINDING: CEA was identified as the only laboratory indicator with a significant difference in both univariate and multivariate analyses.

KEY FINDING: The patient presented with acute respiratory failure as the primary symptom of NMO relapse, which is an atypical presentation.

KEY FINDING: Peripheral nerve grafts (PNGs) can promote the regrowth of respiratory-associated axons after SCI. Combining PNGs with chondroitinase ABC (ChABC) to remove growth inhibitors can enhance functional recovery of the diaphragm.

KEY FINDING: Expression of cRheb selectively in rVRG neurons following cervical hemisection SCI stimulates mTOR pathway activation within transduced cells.

KEY FINDING: ChABC treatment at chronic stages post-cervical contusion injury leads to recovery of normal activity in the ipsilateral hemidiaphragm.