Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.
Showing 61-70 of 95 results
Journal of NeuroEngineering and Rehabilitation, 2015 • November 6, 2015
The present study explored the test-retest reliability of motor performance and brain activation of a novel robot-aided experimental fMRI paradigm at the individual and group-level. The consistency of...
KEY FINDING: Reliability of motor performance was higher during passive than active movements, as seen in lower RMSE for passive movements.
JOURNAL OF NEUROTRAUMA, 2017 • April 15, 2017
The study investigates alterations in brain connectivity in mTBI patients using rsfMRI and relates these alterations to cognitive and behavioral outcomes at 6 months post-injury. The results show that...
KEY FINDING: mTBI patients, regardless of whether they show lesions on standard scans, exhibit alterations in brain network connectivity that correlate with cognitive performance six months post-injury.
PLOS ONE, 2016 • March 8, 2016
This study used resting-state fMRI to investigate changes in cortical sensorimotor connectivity following complete cervical spinal cord injury (SCI). Eleven patients with chronic cervical SCI and nine...
KEY FINDING: SCI patients showed decreased functional connectivity in motor and sensory cortical regions compared to controls, including ipsilateral, contralateral, and interhemispheric regions for left and right precentral ROIs.
Human Brain Mapping, 2016 • March 3, 2016
This study explored structural and functional changes in the spine and brain of SCI patients and their relationship to motor recovery, comparing patients with good and poor recovery to healthy control...
KEY FINDING: Poor recoverers had significantly decreased spinal cord area, cortical thickness in motor areas, and fractional anisotropy in the primary motor cortex compared to good recoverers.
BRAIN, 2016 • April 21, 2016
Embodied neurology is a framework that emphasizes the importance of reciprocal interactions between the nervous system and the body in understanding and treating neurological disorders. The approach i...
KEY FINDING: Reciprocal information flows between the body and the nervous system are crucial for understanding and treating neurological disorders.
Neural Plasticity, 2017 • February 1, 2017
The study aimed to determine if SCI could indirectly impair or reshape the white matter (WM) of the human brain and whether these changes correlate with injury severity, duration, or clinical performa...
KEY FINDING: SCI patients exhibited significant decreases in WM fractional anisotropy (FA) in several brain regions, including the left angular gyrus, right cerebellum, left precentral gyrus, left lateral occipital region, left superior longitudinal fasciculus, left supramarginal gyrus, and left postcentral gyrus.
Spinal Cord Series and Cases, 2017 • February 2, 2017
The study investigated the feasibility of using spinal cord fMRI to assess sexual responses in women with spinal cord injuries (SCI). fMRI responses during audiovisual stimulation, self-stimulation, a...
KEY FINDING: Spinal fMRI responses of the intermediolateral columns were found during audiovisual stimulation in both subjects with incomplete injuries, but not in the subject with a complete injury.
Neuroradiology, 2017 • August 1, 2017
The study aimed to improve the specificity of DTI measurements in assessing SCI by using a subject-specific injury demarcation approach. This involved using DTI tractography to define regions relative...
KEY FINDING: DTI indices obtained from the IRRI region showed the highest specificity to impairment, demonstrating their strong potential as biomarkers for the SCI severity.
NeuroImage: Clinical, 2017 • June 1, 2017
The study revealed atrophy and myelin reductions within major brainstem pathways and nuclei involved in motor and sensory function in chronic traumatic SCI. Atrophy was observed in motor and sensory p...
KEY FINDING: Volume loss was detected in the corticospinal tracts (CSTs) and in the medial lemniscus in SCI patients compared to healthy controls.
Hum Brain Mapp, 2009 • March 1, 2009
This study investigates the feasibility and reliability of using functional electrical stimulation (FES) in an MRI environment to observe brain activity. The experiment involved alternating stimulatio...
KEY FINDING: FES stimulation reliably activates the sensorimotor network, including the contralateral primary motor cortex, somatosensory cortex, and premotor cortex.