Browse the latest research summaries in the field of neuroimaging for spinal cord injury patients and caregivers.
Showing 71-80 of 95 results
Ann Neurol, 2009 • October 1, 2009
The study investigates brainstem MRS as a surrogate marker for spinal cord axonal health in mice with virus-induced demyelination. Brainstem NAA levels correlate with axonal loss and remyelination in ...
KEY FINDING: Brainstem NAA concentrations decreased in both SJL and FVB mice at 90 days post-infection, indicating demyelination.
Multiple Sclerosis, 2010 • January 1, 2010
The study aimed to determine if diffusion tensor imaging (DTI) measures, radial diffusivity (RD) and axial diffusivity (AD), in the cortico-spinal tract (CST) can predict clinical recovery after a spi...
KEY FINDING: Lower baseline radial diffusivity (RD) in the cortico-spinal tract (CST) predicts better clinical outcomes in MS patients after a spinal cord relapse.
J. Magn. Reson. Imaging, 2010 • November 1, 2010
The study aimed to determine if a 3D-MDEFT sequence, typically used for brain morphometry, could also provide reliable measures of spinal cord cross-sectional area (SCA). Images of the brain and cervi...
KEY FINDING: The 3D-MDEFT approach showed similar precision to standard methods for scan-rescan reproducibility of spinal cord area (SCA) measurements.
Brain, 2011 • May 1, 2011
This study investigated the impact of traumatic spinal cord injury (SCI) on structural integrity, cortical reorganization, and disability by assessing anatomical changes in the spinal cord and brain a...
KEY FINDING: Subjects with SCI had a 30% reduced cord area compared to controls, indicating spinal cord atrophy.
Frontiers in Aging Neuroscience, 2017 • September 7, 2017
The study investigated the use of combined SPECT and EEG data to improve the differential diagnosis of amnestic disorders. The researchers aimed to see if combining cerebral perfusion data with EEG c...
KEY FINDING: Combining SPECT with EEG biomarkers improved classification accuracy for aSCC vs. AD (90%), aMCI vs. AD (70%), and AD vs. DCI (100%).
Neural Regeneration Research, 2018 • January 1, 2018
This study reports on a male patient with memory impairment who showed injury of the Papez circuit following TSCI and concomitant mild TBI. DTT revealed injury of the left thalamocortical tract and th...
KEY FINDING: The patient with TSCI and mild TBI showed memory impairment.
J Clin Neurol, 2018 • April 1, 2018
Diffusion-tensor imaging (DTI) is a noninvasive medical imaging tool used to investigate the structure of white matter. The signal contrast in DTI is generated by differences in the Brownian motion of...
KEY FINDING: DTI scalars like FA, AD, RD, MD, and MO can be correlated with clinical information to reveal abnormalities associated with neurological diseases.
NeuroImage: Clinical, 2018 • August 19, 2018
The study investigated early neurodegenerative changes following acute spinal cord injury (SCI) using quantitative MRI (qMRI) and assessed their predictive value for functional recovery. Results showe...
KEY FINDING: Early after SCI, there are decreases in the size of the spinal cord and changes in the cerebellum.
Frontiers in Neurology, 2018 • August 29, 2018
This study investigates the changes in the spinal cord after laminoplasty in patients with cervical myelopathy (CM) using diffusion tensor imaging (DTI). The results indicate that laminoplasty leads t...
KEY FINDING: CM patients showed significant changes in their postoperative diffusion metrics for the anterior ROIs compared with the preoperative measures both at and below the lesion level.
NeuroImage: Clinical, 2019 • January 9, 2019
The study investigates brain functional and structural reorganization in patients with subacute incomplete cervical cord injury (ICCI) using fMRI and voxel-based morphometry. The results suggest that ...
KEY FINDING: ICCI patients exhibited decreased activation in the left postcentral gyrus (postCG), the brainstem (midbrain and right pons) and the right cerebellar lobules IV-VI compared to healthy controls.