Browse the latest research summaries in the field of genetics for spinal cord injury patients and caregivers.
Showing 1,771-1,773 of 1,773 results
Brain, 2011 • April 1, 2011
This study demonstrates that decorin core protein infusion suppresses Sema3A mRNA and protein levels in CNS injury sites, particularly in leptomeningeal fibroblasts within fibrotic scar tissue. Decori...
KEY FINDING: Decorin infusion reduces Sema3A mRNA and protein levels in cerebral cortex scar tissue.
Molecular Therapy, 2011 • February 1, 2011
This study investigates the efficacy of intraspinal delivery of G-CSF using AAV in an ALS mouse model. The results indicate that intraspinal delivery improves motor functions, delays disease progressi...
KEY FINDING: Intraspinal delivery of AAV-G-CSF improved motor functions, delayed disease progression, and increased survival by 10% in SOD-1 (G93A) mice, longer than after systemic delivery.
Molecular Pain, 2010 • December 17, 2010
The study examined behavioral responses to laser stimulation of Aδ- and C-fibers in rats, both before and after RTX-induced ablation. Recovery of behavioral function progressed from proximal (mid-plan...
KEY FINDING: RTX-induced thermal hypoalgesia is sustained longer than previously thought, particularly for Aδ fibers.