Browse the latest research summaries in the field of critical care for spinal cord injury patients and caregivers.
Showing 41-50 of 61 results
The Journal of Spinal Cord Medicine, 2021 • May 1, 2021
Current guidelines recommend artificially elevating MAP to >85 mmHg for 7 days after acute traumatic SCI, based on Level III evidence extrapolated from TBI literature. Significant gaps exist in knowle...
KEY FINDING: Norepinephrine (NE) may be the vasopressor of choice in acute traumatic SCI, potentially offering benefits over phenylephrine (PE) and dopamine (DA).
eLife, 2019 • December 3, 2019
This study establishes a murine model of sepsis with ICU-like interventions to investigate chronic muscle weakness in survivors. The research demonstrates that sepsis survivors have prolonged muscle w...
KEY FINDING: Sepsis survivors exhibit chronic muscle weakness for at least one month, even after muscle mass recovery.
ERJ Open Res, 2020 • January 1, 2020
This study investigated the prevalence and characteristics of home invasive mechanical ventilation (HIMV) in Finland from 2015 to 2019, finding a decrease in prevalence during the study period. The mo...
KEY FINDING: The prevalence of HIMV in Finland decreased from 2.4 in 100,000 in 2015 to 2.0 in 100,000 in 2019.
Surgery, 2023 • January 1, 2023
This study evaluates the impact of early diaphragm pacing (DP) on weaning from mechanical ventilation (MV) and tracheostomy use in cervical spinal cord injury (SCI) patients during the COVID-19 pandem...
KEY FINDING: Diaphragm pacing successfully weaned 82% of patients surviving past 90 days from mechanical ventilation.
Spinal Cord Series and Cases, 2022 • December 1, 2022
This study examines the differences in vital signs and mental status between septic patients with tetraplegia and paraplegia to improve early identification of sepsis in the tetraplegic population. Th...
KEY FINDING: Septic patients with tetraplegia had lower maximum temperature compared to septic patients with paraplegia.
Spine Surg Relat Res, 2023 • June 9, 2023
This retrospective study analyzed 231 patients who underwent SCI surgery between 2017 and 2021 to determine the predictors of delirium after surgery. The study found that age, treatment during the COV...
KEY FINDING: Age ≥73 years, treatment during the COVID-19 pandemic, and psychiatric disorders were identified as independent risk factors for delirium after SCI surgery.
The Journal of Spinal Cord Medicine, 2017 • March 1, 2017
This study examines the use of extracorporeal lung support (ECMO and iLA) in patients with spinal cord injury (SCI) and post-traumatic lung failure. The results suggest that ECMO is a feasible and pot...
KEY FINDING: All 5 ECMO-supported patients were successfully weaned, and one of the two iLA-treated patients was weaned from the device.
Handb Clin Neurol, 2015 • January 1, 2015
Autonomic dysfunction can occur after traumatic brain injury due to damage to the central autonomic network (CAN), affecting the balance of excitatory and inhibitory inputs to ANS effector organs. Isc...
KEY FINDING: Ischemic strokes, especially insular strokes, may cause cardiac autonomic dysregulation, potentially leading to subendocardial hemorrhages and myocardial infarction.
Physiol Rep, 2016 • December 1, 2016
This study investigated the interaction between mechanical ventilation (MV) and spinal cord injury (SCI) on pulmonary inflammation in rats. The researchers measured inflammatory cytokine profiles and ...
KEY FINDING: Mechanical ventilation increased levels of TNF-α, IL-1β, and IL-6, while decreasing IL-10 in the bronchoalveolar lavage (BAL) fluid of rats without spinal cord injury.
Spinal Cord Series and Cases, 2016 • July 14, 2016
This case report describes a unique instance of critical illness myopathy (CIM) in a 23-year-old male who sustained a cervical spine injury and was admitted to the ICU. The patient developed significa...
KEY FINDING: A 23-year-old male with a cervical spine injury developed critical illness myopathy (CIM) while in the ICU, a previously unreported occurrence.