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  4. Time is spine: critical updates for the intensivist

Time is spine: critical updates for the intensivist

Curr Opin Crit Care, 2025 · DOI: 10.1097/MCC.0000000000001245 · Published: April 1, 2025

Spinal Cord InjuryCritical CareSurgery

Simple Explanation

The principle of ‘time is spine’ suggests that early surgical intervention after a spinal cord injury is crucial to improve patient outcomes. This is similar to the idea of ‘time is brain’ in stroke management. Intensivists play a vital role in the initial assessment and management of SCI patients, focusing on stabilizing the spine, monitoring neurological function, managing hemodynamics, and coordinating multidisciplinary care. While early decompression may be beneficial, the timing of surgery should be tailored to the individual patient, considering factors like injury severity, comorbidities, and available resources. Recent studies question the benefits of ultra-early decompression.

Study Duration
Not specified
Participants
Not specified
Evidence Level
Review article

Key Findings

  • 1
    Early decompression (within 24 hours) may improve neurological outcomes, but the evidence is not definitive and may be influenced by study methodology and patient heterogeneity.
  • 2
    Ultra-early decompression (within 12 hours) did not show statistically significant or clinically meaningful neurological improvements at 12 months in a recent study.
  • 3
    The decision regarding surgical timing must consider the specific characteristics of the injury and patient-specific factors that may influence outcomes.

Research Summary

The timing of spinal decompression and hemodynamic management may impact neurological function, however, because of the deficiencies of current studies, individualized, patient-tailored decision-making is critical. A multidisciplinary approach that considers injury severity and patient characteristics is essential for optimal management. Further research is required to refine the timing of surgical intervention and explore additional factors influencing recovery.

Practical Implications

Individualized Treatment Plans

Tailor decompression timing to individual cases, considering patient-specific and systemic factors.

Advanced Monitoring Techniques

Utilize spinal cord pressure monitoring, intraoperative ultrasound, and advanced imaging for targeted intervention.

Optimal Hemodynamic Management

Maintain spinal cord perfusion through vigilant hemodynamic management to prevent further ischemic injury.

Study Limitations

  • 1
    Heterogenous patient populations
  • 2
    Inconsistent treatment protocols
  • 3
    Variable outcome measures

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