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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Critical Care Research

Browse the latest research summaries in the field of critical care for spinal cord injury patients and caregivers.

Showing 21-30 of 61 results

Spinal Cord InjuryCritical CareResearch Methodology & Design

Guidelines for neuroprognostication in adults with traumatic spinal cord injury

Neurocrit Care, 2024 • November 13, 2023

These guidelines provide recommendations about the reliability of acute-phase predictors of mortality, functional outcome, American Spinal Injury Association Impairment Scale grade conversion, and rec...

KEY FINDING: Pathologic findings on magnetic resonance imaging (MRI), neurological level of injury, and severity of injury are moderately reliable predictors of American Spinal Cord Injury Impairment Scale (AIS) improvement.

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Critical CarePulmonology

Phrenic nerve stimulation to prevent diaphragmatic dysfunction and ventilator-induced lung injury

Intensive Care Medicine Experimental, 2023 • December 6, 2023

This review analyzes the current evidence of phrenic nerve stimulation (PNS) for preventing diaphragm weakness and explores the potential protection against ventilator-induced lung injury (VILI) in cr...

KEY FINDING: Therapeutic PNS has been demonstrated as feasible and safe in lung-healthy and critically ill patients.

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Critical CareSurgeryGastroenterology

Stressing over ulcer prophylaxis in the neurocritical trauma patient

Trauma Surg Acute Care Open, 2024 • January 1, 2024

The authors found that the majority of patients received SUP, generally with histamine receptor antagonists. Furthermore, there was no statistically significant difference between the rate of CSGIB wi...

KEY FINDING: Those receiving SUP demonstrated longer hospital and intensive care stays.

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Spinal Cord InjuryCritical CareSurgery

Perceptions of critically ill individuals with acute and chronic spinal cord injury requiring a tracheostomy tube

Spinal Cord Series and Cases, 2024 • February 29, 2024

This study evaluated the perceptions of patients requiring a tracheostomy tube and aimed to identify possible different perceptions in critically ill patients with acute (ASCI) or chronic spinal cord ...

KEY FINDING: Individuals with ASCI reported significantly more frequent pain at initial assessment compared to individuals with CSCI (p ≤0.014).

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Spinal Cord InjuryCritical CareTrauma

Adherence to international guidelines in neurocritical care of cervical traumatic spinal cord injury-a retrospective study

Brain and Spine, 2024 • April 21, 2024

This retrospective study evaluated the impact of implementing the 2013 guidelines for traumatic spinal cord injury (SCI) management on neurocritical care and patient outcomes. The study found improvem...

KEY FINDING: After the implementation of the 2013 guidelines, mean arterial blood pressure (MAP) was significantly higher in patients.

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Spinal Cord InjuryCritical CareAnesthesiology

AIRWAY MANAGEMENT WITH RIGID BRONCHOSCOPE IN ADULT PATIENT DURING CERVICAL SPINE SURGERY: A CASE REPORT

Acta Clin Croat, 2023 • January 1, 2023

The case report presents a patient with SCIWOCTET who underwent cervical spine surgery. Airway management was achieved using a rigid bronchoscope with manual in-line immobilization to minimize cervica...

KEY FINDING: Rigid bronchoscopy with MILI allowed for successful intubation with minimal head and neck movement in a patient with SCIWOCTET.

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Spinal Cord InjuryCritical CareAging

Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture

J. Clin. Med., 2023 • March 20, 2023

This study aimed to develop a risk score for predicting delirium in elderly patients with cervical spinal cord injury (SCI) and/or cervical fracture, using data from a retrospective cohort study of 15...

KEY FINDING: The study identified six key factors that contribute to the risk of delirium: old age (≥80 years), hypoalbuminemia, cervical fracture, major organ injury, dependence on pre-injury mobility, and comorbid diabetes.

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Critical CarePulmonologyNeurology

Effect of mechanical insufflation-exsufflation for ineffective cough on weaning duration in diseases of the peripheral or central nervous system (MEDINE): study protocol for a randomised controlled trial in a neurological weaning centre

BMJ Open, 2023 • January 1, 2023

This study is a single-center randomized controlled trial designed to assess the efficacy of mechanical insufflation-exsufflation (MI-E) in reducing the duration of mechanical ventilation for neurolog...

KEY FINDING: The primary endpoint of this trial is the duration of mechanical ventilation from randomisation until successful weaning.

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Spinal Cord InjuryCritical Care

Adverse Effect of Neurogenic, Infective, and Inflammatory Fever on Acutely Injured Human Spinal Cord

Journal of Neurotrauma, 2023 • December 1, 2023

This study evaluated the effects of neurogenic, inflammatory, and infective fevers on acutely injured human spinal cords, using data from 86 patients with severe traumatic spinal cord injuries. The fi...

KEY FINDING: High fever occurred in 76.7% of patients with acute, severe traumatic spinal cord injuries.

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Critical CareGeneticsMusculoskeletal Medicine

Post‑sepsis chronic muscle weakness can be prevented by pharmacological protection of mitochondria

Molecular Medicine, 2024 • November 7, 2024

This study investigates the causal relationship between mitochondrial abnormalities and chronic post-sepsis muscle weakness, exploring potential therapeutic targets. The findings demonstrate that post...

KEY FINDING: Post-sepsis skeletal muscle weakness develops progressively after the resolution of acute sepsis and is linked to mitochondrial abnormalities.

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