Browse the latest research summaries in the field of brain injury for spinal cord injury patients and caregivers.
Showing 61-70 of 128 results
Biol Psychiatry Cogn Neurosci Neuroimaging, 2021 • March 1, 2021
This study investigated the relationship between regional brain volumes, measured by MRI at 2 weeks post-mTBI, and PTSD outcomes at 3 and 6 months post-injury. Smaller volumes in the insula, superior ...
KEY FINDING: Smaller volumes of the superior frontal, rostral, and caudal anterior cingulate regions were individually predictive of PTSD at 3 months post-injury.
Archives of Rehabilitation Research and Clinical Translation, 2019 • January 1, 2019
The study assessed the feasibility of delivering problem-solving training (PST) to care partners of adults with traumatic injuries or stroke during the inpatient stay. Recruitment was challenging, wit...
KEY FINDING: Delivering a self-management intervention to care partners during the care recipient’s acute hospital stay is feasible for a subset of potential participants.
Rehabilitation Process and Outcome, 2022 • January 1, 2022
This study investigated the feasibility and acceptability of telerehabilitation for individuals with SCI or ABI in Nepal, where access to specialist rehabilitation services is limited. The telerehabil...
KEY FINDING: Telerehabilitation is feasible and acceptable for individuals with SCI or ABI in Nepal, a low- and middle-income country with limited access to specialist rehabilitation services.
Translational Psychiatry, 2023 • January 6, 2023
This study investigated the role of polygenic risk scores (PRS) for PTSD, major depressive disorder (MDD), and neuroticism (NEU) in predicting the development of PTSD following mild traumatic brain in...
KEY FINDING: The PTSD-PRS was significantly associated with an increased risk of PTSD at 6 months post-mTBI.
Cureus, 2023 • January 27, 2023
This systematic review examined the effects of testosterone therapy in men with spinal cord injury (SCI) and traumatic brain injury (TBI). The review found that testosterone therapy, particularly when...
KEY FINDING: Testosterone therapy combined with exercise increased muscle size and strength in men with SCI, while testosterone alone did not show the same effect.
Neural Regeneration Research, 2022 • March 1, 2022
This study aimed to determine the function of KLF7 in stretch- and OGD-induced apoptosis of HT22 cells in vitro, and in TBI-induced hippocampal neuron damage in mice in vivo. The results suggest that ...
KEY FINDING: KLF7 overexpression significantly reduced apoptosis, activated caspase-3 and lactate dehydrogenase, downregulated the expression of Bax and cleaved caspase-3, and increased the expression of βIII-tubulin and Bcl-2 in HT22 cells after stretch injury and oxygen-glucose deprivation.
European Journal of Trauma and Emergency Surgery, 2021 • July 22, 2020
This study analyzed the impact of the COVID-19 quarantine on traumatic brain injury (TBI) cases in Tyrol, Austria, by comparing data from the 2020 lockdown period with the same period in 2016–2019. Th...
KEY FINDING: The weekly number of TBI patients decreased significantly during the strict quarantine in 2020 compared to 2016, 2018, and 2019.
JOURNAL OF NEUROTRAUMA, 2016 • July 15, 2016
The study investigated the relationship between neuropathic pain symptoms, pain severity, and N-acetylaspartate (NAA) levels in brain areas involved in pain processing among individuals with subacute ...
KEY FINDING: Subjects with Moderate Neuropathic Pain had significantly lower insular NAA than the Low or no Neuropathic Pain group.
Mol Neurobiol, 2017 • March 1, 2016
Traumatic CNS injuries present a significant challenge due to their complexity and lack of effective treatments. Secondary injury mechanisms, including immune responses involving cytokines and chemoki...
KEY FINDING: CX3CL1 is mainly produced by endothelial cells and neurons, with its expression elevated in highly vascularized and innervated organs, including the CNS.
The Journal of Spinal Cord Medicine, 2012 • January 1, 2012
This study investigates the relationship between speech-language pathology (SLP) interventions and outcomes for spinal cord injury (SCI) patients, with a focus on those also having traumatic brain inj...
KEY FINDING: SLP treatment factors explain a small amount of variation in cognitive Functional Independence Measure (FIM), participation, and mood.