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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Alternative Medicine Research

Browse the latest research summaries in the field of alternative medicine for spinal cord injury patients and caregivers.

Showing 161-170 of 188 results

Spinal Cord InjuryAlternative MedicineRegenerative Medicine

Buyang Huanwu decoction up-regulates Notch1 gene expression in injured spinal cord

Neural Regeneration Research, 2015 • August 1, 2015

This study investigated the effect of Buyang Huanwu decoction (BYHWD) on the Notch signaling pathway in rats with spinal cord injury (SCI). The results showed that BYHWD increased the expression of No...

KEY FINDING: The expression of Notch1 was increased in the BYHWD group compared with controls at 7, 14, and 28 days after injury.

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Spinal Cord InjuryAlternative MedicineBioinformatics

Transcription Profiling of a Revealed the Potential Molecular Mechanism of Governor Vessel Electroacupuncture for Spinal Cord Injury in Rats

Neurospine, 2022 • September 1, 2022

This study aimed to identify differentially expressed genes (DEGs) by transcriptome analysis to elucidate a potential mechanism by which governor vessel electroacupuncture (GV-EA) promotes neuronal su...

KEY FINDING: GV-EA treatment regulated the expression of 173 mRNA, 260 lncRNA, and 153 circRNA genes altered by SCI.

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Alternative MedicinePharmacologyGastroenterology

Mechanisms of Xiaochaihu Decoction on Treating Hepatic Fibrosis Explored by Network Pharmacology

Disease Markers, 2022 • October 4, 2022

This work provides a systems perspective to study the relationship between Chinese medicines and diseases. The therapeutic efficacy of XCHD on HF was the sum of multitarget and multi-approach effects fro...

KEY FINDING: 164 potential active compounds from XCHD were screened to act on 95 HF-related targets.

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Alternative MedicineNeurologyNeuroplasticity

Electroacupuncture Activates Neuroplasticity in the Motor Cortex and Corticospinal Tract via the mTOR Pathway in a Rat P-MCAO Model

BioMed Research International, 2022 • November 14, 2022

This study demonstrates that electroacupuncture (EA) can significantly improve neurological deficits, reduce cerebral infarct volume, and decrease neuronal damage in a rat model of ischemic stroke (p-...

KEY FINDING: EA significantly reduced Modified Neurological Severity Scores (mNSS), cerebral infarct volume, and apoptosis of neuronal cells in rats with permanent middle cerebral artery occlusion (p-MCAO).

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Alternative MedicineNeurology

Electroacupuncture promotes nerve regeneration and functional recovery in rats with spinal cord contusion through the coordinate interaction of CD4 and BDNF

ibrain, 2022 • July 6, 2022

This study investigates the effects of electroacupuncture (EA) on spinal cord injury (SCI) in rats, focusing on motor function recovery and nerve regeneration. The results indicate that EA improves mo...

KEY FINDING: Electroacupuncture improves motor function recovery in rats after spinal cord injury, as evidenced by increased BBB scores.

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Spinal Cord InjuryAlternative MedicineNeurology

Possible mechanisms of treatment for spinal cord injury repair with tanshinone IIA

Frontiers in Molecular Neuroscience, 2023 • September 21, 2023

Tanshinone IIA, a key component of Danshen, is hypothesized to promote nerve survival and repair after spinal cord injury (SCI) through its anti-inflammatory, antioxidant, and anti-apoptotic effects. ...

KEY FINDING: Tanshinone IIA exhibits anti-inflammatory effects by regulating inflammatory factors and weakening white blood cell activation, potentially alleviating secondary tissue injury after SCI.

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Spinal Cord InjuryAlternative MedicineRegenerative Medicine

Mesenchymal Stem Cells Combined With Electroacupuncture Treatment Regulate the Subpopulation of Macrophages and Astrocytes to Facilitate Axonal Regeneration in Transected Spinal Cord

Neurospine, 2023 • September 25, 2023

The study aimed to determine whether mesenchymal stem cells (MSCs) transplantation combined with electroacupuncture (EA) treatment could decrease the proportion of proinflammatory microglia/macrophage...

KEY FINDING: MSCs+EA treatment reduced the proportion of pro-inflammatory M1 subtype microglia/macrophages and increased the differentiation of anti-inflammatory M2 phenotype cells.

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Alternative MedicineNeurology

Lycium barbarum Extract Enhanced Neuroplasticity and Functional Recovery in 5xFAD Mice via Modulating Microglial Status of the Central Nervous System

CNS Neuroscience & Therapeutics, 2024 • October 30, 2024

This study investigated the effects of Lycium barbarum extract (LBE) on the central nervous system (CNS) in 5xFAD transgenic mice, a model for Alzheimer's disease (AD). The objective was to assess LBE...

KEY FINDING: LBE treatment significantly slowed the decline in cognitive, motor, and visual functions in 5xFAD mice.

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Spinal Cord InjuryAlternative MedicineRegenerative Medicine

Electroacupuncture in the repair of spinal cord injury: inhibiting the Notch signaling pathway and promoting neural stem cell proliferation

Neural Regeneration Research, 2015 • March 1, 2015

This research investigated the effects and mechanisms of electroacupuncture (EA) on spinal cord injury (SCI) repair in rats. EA was applied to specific acupoints after inducing SCI in the rats. The st...

KEY FINDING: Electroacupuncture (EA) decreased the levels of inflammatory factors (TNF-α, IL-1a, IL-6 and IL-10) in rats with spinal cord injuries.

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Alternative MedicineRegenerative MedicineVeterinary Medicine

Electroacupuncture improves microcirculation and neuronal morphology in the spinal cord of a rat model of intervertebral disc extrusion

Neural Regeneration Research, 2015 • February 1, 2015

This study explores the effects of electroacupuncture on spinal cord neuronal injury in a rat model of intervertebral disc extrusion, emphasizing the importance of microcirculation. The results indica...

KEY FINDING: Electroacupuncture significantly increased blood flow in the L1 segment of the spinal cord in rats with intervertebral disc extrusion.

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