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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Alternative Medicine Research

Browse the latest research summaries in the field of alternative medicine for spinal cord injury patients and caregivers.

Showing 91-100 of 188 results

Spinal Cord InjuryAlternative MedicineNeurology

The mechanism of electroacupuncture for treating spinal cord injury rats by mediating Rho/Rho-associated kinase signaling pathway

The Journal of Spinal Cord Medicine, 2021 • July 1, 2021

The study aimed to determine the changes of gene and protein expression through the Rho/ROCK signaling pathway in EA treated spinal cord injury (SCI) rats and to unveil the possible underlying mechani...

KEY FINDING: Electroacupuncture (EA) treatment significantly reduced mRNA and protein expression levels of RhoA and ROCKII in spinal cord injury (SCI) rats.

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Alternative MedicineNeurologyRehabilitation

Unravelling functional neurology: does spinal manipulation have an effect on the brain? - a systematic literature review

Chiropractic & Manual Therapies, 2019 • July 2, 2019

This systematic review evaluated 18 articles to investigate the effect of spinal manipulation (SM) on 'brain function' and its association with clinical benefits. The review found that SM appears to i...

KEY FINDING: Spinal manipulation appears to cause changes in brain function, but these changes are inconsistent across studies.

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Alternative MedicineNeurologyRehabilitation

The Effect of Different Acupuncture Therapies on Neurological Recovery in Spinal Cord Injury: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Evidence-Based Complementary and Alternative Medicine, 2019 • October 27, 2019

This network meta-analysis aimed to determine the effectiveness of various acupuncture therapies for SCI in improving motor function and daily living ability. Preliminary analysis showed that except f...

KEY FINDING: Exercise combined with electro-acupuncture (EA) is more effective than exercise alone in improving the ASIA motor score.

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Alternative MedicinePharmacologyPain Management

Role of spinal adenosine A1 receptors in the analgesic effect of electroacupuncture in a rat model of neuropathic pain

Journal of International Medical Research, 2019 • April 1, 2019

The study aimed to determine the role of spinal adenosine A1 receptors (A1Rs) in the analgesic effects of electroacupuncture (EA) for neuropathic pain using a rat model. Results showed that EA increas...

KEY FINDING: Electroacupuncture (EA) at the zusanli acupoint increases adenosine levels in the L4–6 spinal cord of rats.

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Alternative MedicinePain ManagementGenetics

Synaptotagmin 1 Is Involved in Neuropathic Pain and Electroacupuncture-Mediated Analgesic Effect

International Journal of Molecular Sciences, 2020 • January 31, 2020

The study demonstrates that Syt-1 plays a role in the development of neuropathic pain. Electroacupuncture can alleviate neuropathic pain, possibly by suppressing Syt-1 protein expression in the spinal...

KEY FINDING: Syt-1 antibody blockade and siRNA silencing increased pain thresholds in SNI rats.

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Alternative MedicineHealthcareRehabilitation

Thoracic adverse events following spinal manipulative therapy: a systematic review and narrative synthesis

JOURNAL OF MANUAL & MANIPULATIVE THERAPY, 2020 • February 12, 2020

This systematic review synthesized evidence of thoracic adverse events (AE) following spinal manipulative therapy (SMT). It included 21 cases published in 19 studies, highlighting instances of AE afte...

KEY FINDING: Serious thoracic AE including permanent neurological deficit and death have been reported following SMT, even though causality cannot be confirmed.

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Alternative MedicinePain ManagementGenetics

Electroacupuncture Treatment Suppresses Transcription Factor IRF8 in Spinal Cord of Rats with Spared Nerve Injury

Pain Research and Management, 2020 • April 10, 2020

This study investigates the effect of 2 Hz electroacupuncture (EA) on neuropathic pain in rats with spared nerve injury (SNI), focusing on the role of interferon regulatory factor 8 (IRF8) and CX3CRl ...

KEY FINDING: Spared nerve injury (SNI) significantly increased spinal IRF8 and CX3CRl mRNA and protein expression in rats.

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Spinal Cord InjuryAlternative MedicineNeurology

Effect of Electroacupuncture Treatment at Dazhui (GV14) and Mingmen (GV4) Modulates the PI3K/AKT/mTOR Signaling Pathway in Rats after Spinal Cord Injury

Neural Plasticity, 2020 • January 21, 2020

This study investigates the therapeutic effect of electroacupuncture (EA) on spinal cord injury (SCI) in rats and elucidates the effect of EA on the mTOR and PI3K/AKT/mTOR signaling pathway. The resul...

KEY FINDING: EA improves locomotor function in SCI rats, as evidenced by increased BBB scale scores compared to the model group.

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Spinal Cord InjuryAlternative MedicineGenetics

Comprehensive analysis of the differential expression profile of microRNAs in rats with spinal cord injury treated by electroacupuncture

Molecular Medicine Reports, 2020 • April 22, 2020

The study investigated the effects of electroacupuncture (EA) on microRNA (miRNA) expression profiles in spinal cord injury (SCI) rats to understand the potential mechanisms involved in SCI recovery. ...

KEY FINDING: Electroacupuncture (EA) treatment improved hindlimb motor function in spinal cord injury (SCI) rats, as indicated by higher Basso, Beattie and Bresnahan (BBB) scores.

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Alternative MedicineNeurologyRehabilitation

Effectiveness of electroacupuncture (EA) for the treatment of urinary incontinence (UI) in patients with spinal cord injury (SCI): A protocol of systematic review of randomized controlled trials

Medicine, 2020 • July 24, 2020

This systematic review aims to evaluate the effectiveness and safety of electroacupuncture (EA) for treating urinary incontinence (UI) in patients with spinal cord injury (SCI). The review will includ...

KEY FINDING: This study will summarize the most recent evidence to assess the effectiveness and safety of EA for the treatment of UI in patients with SCI.

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