Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,431-11,440 of 12,052 results
Conf Proc IEEE Eng Med Biol Soc, 2011 • January 1, 2011
The study compared robot-driven epidural stimulation with conventional stimulation in spinalized rats using a trunk-based neurorobotic system. The results indicated that robot-driven stimulation led t...
KEY FINDING: Robot-driven epidural stimulation led to significantly greater improvements in AOB scores compared to conventional stimulation and control groups.
IEEE Int Conf Rehabil Robot, 2011 • January 1, 2011
This paper introduces a powered lower limb orthosis designed to aid walking in paraplegic individuals by providing assistive torques at the hip and knee joints, controlled via upper-body movements. Ex...
KEY FINDING: The powered orthosis and control system can effectively provide walking within parallel bars.
Top Spinal Cord Inj Rehabil, 2011 • January 1, 2011
The article highlights significant disparities in rehabilitation outcomes among individuals with spinal cord injury (SCI), particularly affecting vulnerable populations such as racial and ethnic minor...
KEY FINDING: Socioeconomic status is strongly associated with variations in mortality and morbidity among individuals with SCI, with low income and education increasing mortality risk.
Cell Medicine, 2011 • January 1, 2011
This study explored the mechanisms for functional recovery in SCI rats after intravenous transplantation of MSCs derived from human umbilical cord blood. MSC-treated rats showed a modest but significa...
KEY FINDING: MSCs transplantation resulted in modest but significant improvement in locomotor function of SCI rats.
PLoS ONE, 2010 • December 30, 2010
The study investigated the effects of transplanting human embryonic neural progenitors (hENPs), with or without Neurogenin-2 (Ngn2) expression, into rats with severe spinal cord injuries. Results show...
KEY FINDING: Transplantation of hENPs expressing Ngn2 improved motor recovery after severe spinal cord compression in rats.
Surgical Neurology International, 2010 • December 25, 2010
This review article discusses the potential of stem cell transplantation for spinal cord regeneration, highlighting the limitations of current management options for SCI and the underlying mechanisms ...
KEY FINDING: Olfactory ensheathing cells (OECs) appear to be the most promising stem cell type for spinal cord regeneration due to their supportive role in axonal regeneration.
PLoS ONE, 2010 • December 20, 2010
This study aimed to assess the synergistic protective effect of human mesenchymal stem cells (hMSCs) and pituitary adenylate cyclase-activating polypeptide (PACAP) on functional recovery in rats with ...
KEY FINDING: Delayed treatment with PACAP and hMSCs at day 7 post SCI increased the remaining neuronal fibers in the injured spinal cord, leading to better locomotor functional recovery in SCI rats when compared to treatment only with PACAP or hMSCs.
Molecular Pain, 2010 • December 17, 2010
The study examined behavioral responses to laser stimulation of Aδ- and C-fibers in rats, both before and after RTX-induced ablation. Recovery of behavioral function progressed from proximal (mid-plan...
KEY FINDING: RTX-induced thermal hypoalgesia is sustained longer than previously thought, particularly for Aδ fibers.
Cell Mol Neurobiol, 2011 • December 14, 2010
The study investigated the optimal location and timing for neural stem cell (NSC) transplantation in rats with transected spinal cords to improve neurological function. NSC transplantation into spinal...
KEY FINDING: NSC transplantation in the spinal cords rostral to the transection site at the subacute stage (7 days post operation) resulted in significant improvement in hindlimb locomotor functions.
Eur Spine J, 2011 • December 5, 2010
This study investigated the effect of cervical radiculopathy on the cutaneous silent period (CSP), an electrophysiological measure of spinal inhibitory reflexes. The results showed that the CSP is pre...
KEY FINDING: The cutaneous silent period (CSP) was preserved in most patients with cervical radiculopathy, regardless of which finger was stimulated.