Browse the latest research summaries in the field of spinal cord injury for spinal cord injury patients and caregivers.
Showing 2,571-2,580 of 7,812 results
International Journal for Equity in Health, 2021 • December 1, 2021
This study aimed to understand the pathways through which SES influences loneliness in a large sample of persons with physical disabilities, namely SCI. This study highlighted the importance of second...
KEY FINDING: The study demonstrated robust associations between socioeconomic status and all potential mediators, whereby higher socioeconomic status was associated with better health, participation and psychosocial resources.
The Journal of Spinal Cord Medicine, 2023 • March 1, 2023
The review highlights the potential utility of ALP and B-ALP in assessing changes in bone turnover in humans with SCI, but evidence in animal models is less compelling. The association between ALP and...
KEY FINDING: Evidence regarding changes in ALP levels in individuals with SCI compared to controls is conflicting.
International Journal of General Medicine, 2021 • December 13, 2021
This study investigated the therapeutic potential of UC-MSC transplantation for SCI, using DTI to assess microstructural changes in the spinal cord. The experimental group received UC-MSC transplantat...
KEY FINDING: Significant differences were observed in fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values before and after treatment in the experimental group (P < 0.05).
Biomedicines, 2021 • December 3, 2021
This study investigates the effects of repetitive trans-spinal magnetic stimulation (rTSMS) on spinal cord injury (SCI) in rat models, using both penetrating and contusive injury models to mimic human...
KEY FINDING: rTSMS treatment induces locomotor recovery after a complete transection of the spinal cord in rats, specifically observed at 30 and 60 days post-SCI.
The Journal of Spinal Cord Medicine, 2022 • January 1, 2022
This study evaluated the impact of the COVID-19 pandemic on access to resources and psychological well-being in individuals with SCI, comparing data collected before and during the pandemic. The findi...
KEY FINDING: The study found that a significant percentage of participants reported limited access to regular activities, healthcare information, PPE, food, and medication refills during the COVID-19 pandemic.
Bioactive Materials, 2022 • October 20, 2021
This study presents a novel approach to spinal cord injury (SCI) repair by constructing a niche-specific spinal white matter-like tissue (WMLT) using decellularized optic nerve (DON) loaded with neuro...
KEY FINDING: The white matter-like tissue (WMLT) transplantation group showed significant improvement in coordinated motor functions compared with the control groups.
Brain Sciences, 2021 • December 10, 2021
The systematic review summarizes the state-of-the-art robotic-assisted rehabilitation treatments available for patients suffering from cervical SCI. Robotic-assisted training is still experimental, bu...
KEY FINDING: Robotic-assisted training is safe, tolerable, and feasible in the rehabilitation of SCI patients, but this has been primarily investigated in patients with other neurological diseases.
International Journal of Molecular Sciences, 2021 • December 17, 2021
This review focuses on microglia-astrocyte crosstalk and glial-neuronal interactions in an acute inflammatory response after spinal cord injury (SCI). The review highlights the time-dependent transform...
KEY FINDING: Proliferating microglia are a key cellular component of the microglial scar which develops during the first week post-SCI to protect neural tissue.
Journal of NeuroEngineering and Rehabilitation, 2021 • December 1, 2021
This feasibility study evaluated the use of a free-standing robotic exoskeleton (REX) for physiotherapy in patients with spinal cord injury (SCI). The study assessed the acceptability, recruitment rat...
KEY FINDING: The study demonstrated that a 12-week intervention program using a free-standing exoskeleton for weightbearing exercise in those with severe mobility impairment, as a result of SCI, is acceptable, safe and achievable.
Frontiers in Neuroscience, 2021 • December 8, 2021
This review explores the role of sensory circuit remodeling in movement recovery after spinal cord injury (SCI), emphasizing the importance of sensorimotor integration and cortical plasticity. The rev...
KEY FINDING: Proprioceptive feedback is indispensable for both driving functional recovery as well as for maintaining that recovered function after SCI.