Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 181-190 of 702 results
Ann Neurol, 2023 • December 1, 2023
This study developed a 1-year functional dependency prediction model for patients with DoC after TBI using data from TBI-MS and TRACK-TBI. The model incorporates age, severity of neurological impairme...
KEY FINDING: A combination of variables (age, IVH, followed commands within 5 days of injury, and severity of functional and motor impairment at admission to rehabilitation) produces a well-calibrated estimate of the probability of functional dependency at 1-year.
Lancet Neurol, 2023 • August 1, 2023
This study delivers the first, to our knowledge, clinical trial of a rationally designed pharmacological treatment for neural repair in chronic SCI. AXER-204 appeared safe and reached targeted CSF con...
KEY FINDING: AXER-204 was found to be safe and well-tolerated in patients with chronic cervical SCI at the doses tested.
The Journal of Spinal Cord Medicine, 2024 • January 1, 2024
This study evaluated the criterion and construct validity of the Trunk Assessment Scale for Spinal Cord Injury (TASS) and the Trunk Control Test for individuals with Spinal Cord Injury (TCT-SCI). The ...
KEY FINDING: A moderate correlation was found between the TASS and the TCT-SCI, indicating they both measure trunk function but have different focuses.
Tomography, 2023 • October 27, 2023
This case report presents a patient with Conus Medullaris Syndrome (CMS) resulting from a T12 burst fracture, leading to compression of the proximal conus medullaris (CM). The patient underwent surgi...
KEY FINDING: A high-riding injury site in CMS, proximal to the tip of the conus medullaris, correlates with a more pronounced clinical presentation of upper motor neuron signs (UMNS).
Rehabilitation, 2024 • August 21, 2023
The aim of this study was to synthesize the findings of qualitative meta-syntheses (QMS) on return to work (RTW) of people with different chronic illnesses and to develop a generic RTW model that can ...
KEY FINDING: RTW is a multifactorial and highly interactive multistakeholder process, embedded in the individual’s life and working history, as well as in a determined social and societal context.
The Journal of Spinal Cord Medicine, 2025 • January 1, 2025
The bibliometric analysis shows a rapid increase in SRMA applications in SCI research. The study identifies key methodological concerns among a randomly selected set of articles. The authors provide g...
KEY FINDING: The use of SRMA in SCI research has increased rapidly since 2009, with an annual growth rate of approximately 15%.
Global Spine Journal, 2024 • March 1, 2024
This guideline updates the 2013 AANS/CNS recommendations on hemodynamic management of patients with acute traumatic SCI, incorporating literature published since 2011. The guideline development group ...
KEY FINDING: The guideline suggests that MAP should be augmented to at least 75-80 mmHg as the “lower limit” in acute traumatic SCI patients.
BMC Musculoskeletal Disorders, 2023 • July 27, 2023
This case report presents a 38-year-old female patient with Klippel-Feil syndrome (KFS) who developed Brown-Sequard syndrome (BSS) after a minor traumatic episode. The patient underwent surgical treat...
KEY FINDING: A patient with Klippel-Feil syndrome (KFS) developed Brown-Sequard syndrome (BSS) following a minor trauma.
The Journal of Spinal Cord Medicine, 2024 • January 1, 2024
This systematic review aimed to identify and recommend QoL instruments for individuals with SCI/D based on measurement properties. The review found a need for instruments with high-quality evidence fo...
KEY FINDING: No single QoL instrument can be highly recommended as the most suitable for individuals with SCI/D due to limitations in current evidence.
The Journal of Spinal Cord Medicine, 2025 • September 19, 2023
This study statistically confirms the structural validity of the Trunk Assessment Scale for Spinal Cord Injury (TASS) using Rasch analysis. The TASS is a unidimensional scale with good person and item...
KEY FINDING: The TASS was observed to be a unidimensional and highly reproducible scale of item difficulty hierarchy that sufficiently identifies the superiority of the examinee’s ability.