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  4. Brown Sequard syndrome in a patient with Klippel-Feil syndrome following minor trauma: a case report and literature review

Brown Sequard syndrome in a patient with Klippel-Feil syndrome following minor trauma: a case report and literature review

BMC Musculoskeletal Disorders, 2023 · DOI: https://doi.org/10.1186/s12891-023-06760-9 · Published: July 27, 2023

OrthopedicsSpinal DisordersResearch Methodology & Design

Simple Explanation

This case report discusses a patient with Klippel-Feil syndrome (KFS) who experienced Brown-Sequard syndrome (BSS) after a minor injury. KFS is a congenital condition involving abnormal fusion of cervical vertebrae. The patient, a 38-year-old woman with KFS type III, developed numbness and weakness in her limbs after a fall. She was treated with surgery, hyperbaric oxygen, and rehabilitation. The study highlights that individuals with KFS are more susceptible to spinal cord injuries from even minor trauma due to the altered biomechanics of their cervical spine.

Study Duration
Not specified
Participants
A 38-year-old female patient with KFS type III
Evidence Level
Level 4: Case Report and Literature Review

Key Findings

  • 1
    A patient with Klippel-Feil syndrome (KFS) developed Brown-Sequard syndrome (BSS) following a minor trauma.
  • 2
    Surgical intervention, combined with comprehensive treatment and rehabilitation, led to significant improvement in the patient's condition, improving from grade B to grade D on the ASIA Impairment Scale.
  • 3
    The cervical deformity in patients with KFS can alter the overall mechanical activity of the spine, increasing the chance of spinal cord injury (SCI) following trauma.

Research Summary

This case report presents a 38-year-old female patient with Klippel-Feil syndrome (KFS) who developed Brown-Sequard syndrome (BSS) after a minor traumatic episode. The patient underwent surgical treatment, hyperbaric oxygen therapy, rehabilitation, and neurotrophic drugs, resulting in significant improvement in her symptoms and functional abilities. The case highlights the increased risk of spinal cord injury (SCI) in individuals with KFS, even from minor trauma, due to the altered biomechanics of the cervical spine.

Practical Implications

Increased Awareness

Clinicians should be aware of the heightened risk of SCI in KFS patients, even after minor trauma.

Protective Measures

KFS patients should take extra precautions in their daily lives to reduce the risk of trauma.

Early Surgical Intervention

Prompt surgical intervention, followed by comprehensive rehabilitation, may lead to better outcomes for KFS patients with SCI.

Study Limitations

  • 1
    Single case report limits generalizability.
  • 2
    Lack of detailed long-term follow-up data.
  • 3
    Limited information on the specific mechanism of injury.

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