Physiology Research

KEY FINDING: Testing MEPs were not diminished in healthy subjects with or without typical rate-sensitive H-reflex depression, or in subjects with sensory-impaired SCI.

KEY FINDING: The fundamental hypothesis guiding this study is that repetitive exposure to AIH (10 sessions in 2 weeks) will enhance walking recovery in ambulatory and non-ambulatory persons with subacute SCI, presumably by augmenting neural plasticity.

KEY FINDING: Carotid denervation leads to more severe hypoxia-induced hypotension compared to sham rats.

KEY FINDING: Combining high-frequency epidural stimulation (HF-EDS) with GABA and glycine receptor antagonists (GABAzine and strychnine) significantly increased phrenic motor output compared to HF-EDS alone.

KEY FINDING: Neurological recovery was highly significant at 6 months based on ASIA scores.

KEY FINDING: Free-running EMG and triggered EMG are highly useful for identifying lumbosacral roots during surgery.

KEY FINDING: In healthy rats, electrical stimulation of the motor cortex evoked reliable spike activity in the spinal cord at short latencies (10-12 ms) and longer latencies (20-60 ms).

KEY FINDING: Orthostatic hypotension occurred within each level and AIS classification of spinal cord injury, indicating it's not solely predictable by injury severity.

KEY FINDING: Strong neurophysiological evidence of discomplete spinal cord injury was found in 17% (4/23) of participants.

KEY FINDING: The exercise group showed no significant changes in weight, fat-free mass, lean body mass, and percent fat mass after the 52-week program.