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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Pediatrics Research

Browse the latest research summaries in the field of pediatrics for spinal cord injury patients and caregivers.

Showing 131-140 of 140 results

Spinal Cord InjuryNeurologyPediatrics

Functional electrical stimulation cycling in youth with spinal cord injury: A review of intervention studies

The Journal of Spinal Cord Medicine, 2014 • May 1, 2014

This review assessed the evidence for FESC intervention in youth with SCI, finding six intervention studies that met the inclusion criteria. The studies were evaluated for methodological quality and l...

KEY FINDING: FESC appears to be a safe intervention for youth with SCI, with no reported increase in knee/hip injury or hip displacement.

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OncologyPediatricsRehabilitation

Early rehabilitation improves neurofunctional outcome after surgery in children with spinal tumors

Neural Regeneration Research, 2014 • January 1, 2014

This retrospective study evaluated the impact of early rehabilitation on neurofunctional outcomes in 70 pediatric patients who underwent spinal tumor surgery. The patients received rehabilitation trea...

KEY FINDING: Early rehabilitation significantly improved sensory function, motor function, and activity of daily living in pediatric children after spinal tumor surgery.

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Spinal Cord InjuryPediatricsRehabilitation

Case Report: Capitalizing on Development and Activity-Dependent Plasticity, an Interaction With Pediatric-Onset Spinal Cord Injury

Frontiers in Pediatrics, 2022 • March 29, 2022

This case report details the progress of an infant with a cervical spinal cord injury (SCI) who received activity-based restorative therapies (ABRT) after receiving traditional therapies with limited ...

KEY FINDING: The child demonstrated improved trunk control, progressing from needing support to sit upright to sitting independently without support for extended periods.

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Spinal Cord InjuryPediatricsRehabilitation

Spinal Cord Injury at Birth, Expected Medical and Health Complexity in Chronic Injury Guided Anew by Activity-Based Restorative Therapy: Case Report

Frontiers in Psychology, 2022 • April 7, 2022

This case report details the outcomes of activity-based restorative therapy (ABRT) in an infant with cervical spinal cord injury (SCI) at birth, resulting in paralysis. After 59 sessions of ABRT, the ...

KEY FINDING: After 59 sessions of ABRT, the child demonstrated significant improvements in trunk control and arm function.

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Spinal Cord InjuryNeurologyPediatrics

Case report: training neck and head control in children with chronic paralysis due to acute flaccid myelitis

Front. Rehabil. Sci., 2023 • May 19, 2023

This case series presents proof of concept for the application of interventions targeting pre-injury neuromuscular head control. Each patient progressed in head control; however, patients who returned...

KEY FINDING: Children with SCI and chronic paralysis due to AFM can begin to develop head control through a multiphase approach when paired with activity-based restorative therapies.

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Assistive TechnologyPediatrics

Enhancing walking efficiency of adolescents with neurological impairments using an exosuit for ambulatory activities of daily living

Front. Robot. AI, 2024 • March 13, 2024

This cross-sectional study investigated the potential of the Myosuit, a cable-driven exosuit, to enhance walking efficiency in adolescents with neurological impairments during ambulatory activities of...

KEY FINDING: Five out of six participants completed the walking course in less time with the exosuit's assistance, although this reduction was not statistically significant (p=0.08), it showed a large effect size (d=0.88).

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PhysiologyVeterinary MedicinePediatrics

Quantitative analysis of motor evoked potentials in the neonatal lamb

Scientific Reports, 2017 • November 1, 2017

This study aimed to evaluate the feasibility and reliability of standardized motor evoked potential (MEP) recording and analysis in neonatal lambs. The researchers developed an algorithm for MEP quant...

KEY FINDING: MEPs could be easily recorded in neonatal lambs using transcranial motor cortex stimulation.

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GastroenterologyPediatrics

Vedolizumab use after failure of TNF-α antagonists in children and adolescents with inflammatory bowel disease

BMC Gastroenterology, 2018 • September 3, 2018

This study evaluates the use of vedolizumab in Austrian pediatric patients with IBD who had previously failed TNF-α antagonist treatment. The results suggest that vedolizumab can be an effective treat...

KEY FINDING: In the UC group, complete clinical remission was achieved at weeks 2, 6, and 14 in 2/5, 1/5 and 1/5 patients respectively; partial response was observed in one patient at week 2.

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PhysiologyNeurologyPediatrics

Curcumin: Novel Treatment in Neonatal Hypoxic-Ischemic Brain Injury

Frontiers in Physiology, 2019 • November 13, 2019

This study investigated the neuroprotective effects of curcumin in a neonatal mouse model of hypoxic-ischemic (HI) brain injury. The researchers explored different administration times and dosages of ...

KEY FINDING: Curcumin administration prior to HIE in neonatal mice elevated cell and tissue loss, as well as glial activation compared to HI alone.

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Critical CarePediatricsPublic Health

Morbidity and Mortality in Critically Ill Children. II. A Qualitative Patient-Level Analysis of Pathophysiologies and Potential Therapeutic Solutions

Crit Care Med, 2020 • June 1, 2020

This study identified the major causes of morbidity and mortality in critically ill children using detailed assessments of individual patients. Low cardiac output and cardiac arrest, inflammation-rela...

KEY FINDING: The most common problems were related to poor delivery of essential substances like oxygen to the body, inflammation, and direct injury to tissues, especially the brain.

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