Browse the latest research summaries in the field of pediatrics for spinal cord injury patients and caregivers.
Showing 131-140 of 140 results
The Journal of Spinal Cord Medicine, 2014 • May 1, 2014
This review assessed the evidence for FESC intervention in youth with SCI, finding six intervention studies that met the inclusion criteria. The studies were evaluated for methodological quality and l...
KEY FINDING: FESC appears to be a safe intervention for youth with SCI, with no reported increase in knee/hip injury or hip displacement.
Neural Regeneration Research, 2014 • January 1, 2014
This retrospective study evaluated the impact of early rehabilitation on neurofunctional outcomes in 70 pediatric patients who underwent spinal tumor surgery. The patients received rehabilitation trea...
KEY FINDING: Early rehabilitation significantly improved sensory function, motor function, and activity of daily living in pediatric children after spinal tumor surgery.
Frontiers in Pediatrics, 2022 • March 29, 2022
This case report details the progress of an infant with a cervical spinal cord injury (SCI) who received activity-based restorative therapies (ABRT) after receiving traditional therapies with limited ...
KEY FINDING: The child demonstrated improved trunk control, progressing from needing support to sit upright to sitting independently without support for extended periods.
Frontiers in Psychology, 2022 • April 7, 2022
This case report details the outcomes of activity-based restorative therapy (ABRT) in an infant with cervical spinal cord injury (SCI) at birth, resulting in paralysis. After 59 sessions of ABRT, the ...
KEY FINDING: After 59 sessions of ABRT, the child demonstrated significant improvements in trunk control and arm function.
Front. Rehabil. Sci., 2023 • May 19, 2023
This case series presents proof of concept for the application of interventions targeting pre-injury neuromuscular head control. Each patient progressed in head control; however, patients who returned...
KEY FINDING: Children with SCI and chronic paralysis due to AFM can begin to develop head control through a multiphase approach when paired with activity-based restorative therapies.
Front. Robot. AI, 2024 • March 13, 2024
This cross-sectional study investigated the potential of the Myosuit, a cable-driven exosuit, to enhance walking efficiency in adolescents with neurological impairments during ambulatory activities of...
KEY FINDING: Five out of six participants completed the walking course in less time with the exosuit's assistance, although this reduction was not statistically significant (p=0.08), it showed a large effect size (d=0.88).
Scientific Reports, 2017 • November 1, 2017
This study aimed to evaluate the feasibility and reliability of standardized motor evoked potential (MEP) recording and analysis in neonatal lambs. The researchers developed an algorithm for MEP quant...
KEY FINDING: MEPs could be easily recorded in neonatal lambs using transcranial motor cortex stimulation.
BMC Gastroenterology, 2018 • September 3, 2018
This study evaluates the use of vedolizumab in Austrian pediatric patients with IBD who had previously failed TNF-α antagonist treatment. The results suggest that vedolizumab can be an effective treat...
KEY FINDING: In the UC group, complete clinical remission was achieved at weeks 2, 6, and 14 in 2/5, 1/5 and 1/5 patients respectively; partial response was observed in one patient at week 2.
Frontiers in Physiology, 2019 • November 13, 2019
This study investigated the neuroprotective effects of curcumin in a neonatal mouse model of hypoxic-ischemic (HI) brain injury. The researchers explored different administration times and dosages of ...
KEY FINDING: Curcumin administration prior to HIE in neonatal mice elevated cell and tissue loss, as well as glial activation compared to HI alone.
Crit Care Med, 2020 • June 1, 2020
This study identified the major causes of morbidity and mortality in critically ill children using detailed assessments of individual patients. Low cardiac output and cardiac arrest, inflammation-rela...
KEY FINDING: The most common problems were related to poor delivery of essential substances like oxygen to the body, inflammation, and direct injury to tissues, especially the brain.