Browse the latest research summaries in the field of neurorehabilitation for spinal cord injury patients and caregivers.
Showing 31-40 of 344 results
Front. Rehabil. Sci., 2023 • June 29, 2023
Neurorehabilitation is enhanced by targeting beneficial plasticity in the central nervous system (CNS). Skilled behaviors are maintained by distributed networks called heksors, and rehabilitation aims ...
KEY FINDING: Operant down-conditioning of the soleus H-reflex in people with spinal cord injury resulted in faster and more symmetrical walking, with improvements in EMG activity and reports of enhanced daily walking abilities.
Lancet Neurol, 2023 • August 1, 2023
This study delivers the first, to our knowledge, clinical trial of a rationally designed pharmacological treatment for neural repair in chronic SCI. AXER-204 appeared safe and reached targeted CSF con...
KEY FINDING: AXER-204 was found to be safe and well-tolerated in patients with chronic cervical SCI at the doses tested.
Journal of Neural Engineering, 2023 • September 12, 2023
This study investigates the effects of neuron-specific optogenetic spinal stimulation on forelimb recovery, axonal growth, and vasculature in rats with cervical SCI. The results demonstrate that neuro...
KEY FINDING: Neuron-specific optogenetic spinal stimulation significantly enhances recovery of skilled forelimb reaching in rats with cervical SCI.
Front. Hum. Neurosci., 2023 • July 21, 2023
Exercise and physical activity influence neuroplastic changes in individuals with various neurological diagnoses including PD, Stroke, TBI and SCI. Combining exercise with neuromodulation can amplify ...
KEY FINDING: Exercise enhances neuroplasticity by increasing BDNF, IGF-1, and VEGF production, creating a neural environment primed for change in neurological disorders and injuries.
Journal of NeuroEngineering and Rehabilitation, 2023 • July 26, 2023
The study evaluated the safety, clinical feasibility, and usability of a novel arm rehabilitation device (RobExReha) combining a robotic arm and augmented reality serious game for neurorehabilitation....
KEY FINDING: The RobExReha system was found to be safe and feasible for patients and therapists in a neurorehabilitation setting.
Frontiers in Molecular Neuroscience, 2023 • August 7, 2023
This study investigated the therapeutic effects and underlying mechanisms of HAP1 on spinal cord injury in mice. The administration of HAP1 significantly improved neurological function in SCI mice. Th...
KEY FINDING: Recombinant HAP1 (r-HAP1) improves neurological function rehabilitation after SCI and increases Tuj expression in the injured spinal cord.
Front. Rehabil. Sci., 2023 • August 8, 2023
This editorial highlights the role of non-invasive stimulation in neurorehabilitation for various neurological conditions. It emphasizes the potential of combining peripheral and central stimulation t...
KEY FINDING: Motor point mapping, along with standard measures, may predict motor recovery and aid in developing individualized treatment plans for traumatic cervical spinal cord injuries.
European Journal of Medical Research, 2023 • August 3, 2023
This study investigates the effects of ferrostatin-1 on neurological function in mice after SCI, assessing neurophysiological performance 28 days post-SCI. The cEMP results demonstrated that the cEMP ...
KEY FINDING: Ferrostatin-1 promoted the rehabilitation of cortical evoked motor potential and BMS scores, synchronized with improvement in the histological manifestation of neuron survival and scar formation.
PLoS ONE, 2023 • October 5, 2023
This systematic review and meta-analysis examined the effects of rebound exercise on balance and mobility in individuals with neurological disorders. Five studies were included in the review, and thre...
KEY FINDING: Rebound exercise significantly improves mobility in people with neurological disorders. Participants in the rebound group walked quicker by an average of 6.08 seconds.
European Journal of Physical and Rehabilitation Medicine, 2024 • February 1, 2024
This study focused on adapting the Modified Barthel Index (MBI) for use in Greece and evaluating its reliability and validity within a Greek neuro-rehabilitation population. The MBI underwent a thorou...
KEY FINDING: The study rejected the unidimensionality of the MBI, adopting a two-factor solution: Transfers and Activities of Daily Living, and Mobility.