Neuroplasticity Research

KEY FINDING: The combined therapy significantly enhanced the neuroanatomical plasticity of major descending spinal tracts such as corticospinal and serotonergic-spinal pathways.

KEY FINDING: Serum BDNF significantly increased at high exercise intensities compared to moderate intensities and post-exercise.

KEY FINDING: Both 2 and 4 weeks of ch'abc treatment significantly increased the number of rubrospinal tract (RuST) neurons with axons below the lesion.

KEY FINDING: CST collateral formation begins within the first 10 days after spinal cord injury, and these collaterals can persist for at least 24 weeks.

KEY FINDING: Operant conditioning protocols can induce specific changes (up- or down-regulation) in targeted spinal reflexes, as demonstrated in various animal models and humans.

KEY FINDING: Greater BOLD activity was found within the C6–C8 levels of the ipsilateral spinal cord during a complex motor sequence learning task compared to a simple one.

KEY FINDING: Short-term IH administration enhances respiratory function in humans with SCI.

KEY FINDING: α and β ERD evolution after SCI is negatively correlated with the clinical progression of the patients during the first months after the injury.

KEY FINDING: Adaptive spinal training requires adequate and appropriate afferent input to modulate spinal circuitry, like the central pattern generator (CPG), for rhythmic locomotor activities with proprioceptive and sensory feedback.

KEY FINDING: ABRT components improve functional mobility and reverse negative body composition changes after SCI, reducing cardiovascular and metabolic disease risk factors.