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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Neuroplasticity Research

Browse the latest research summaries in the field of neuroplasticity for spinal cord injury patients and caregivers.

Showing 151-153 of 153 results

NeurologyGeneticsNeuroplasticity

Long-Term Gliosis and Molecular Changes in the Cervical Spinal Cord of the Rhesus Monkey after Traumatic Brain Injury

JOURNAL OF NEUROTRAUMA, 2010 • March 1, 2010

The study examined molecular changes in the cervical spinal cord of rhesus monkeys after traumatic brain injury (TBI), focusing on long-term effects up to 12 months post-lesion. Key findings include i...

KEY FINDING: There were significant increases in MHC-II and ERK1/2 immunoreactivity in the lateral corticospinal tract (LCST) of the cervical spinal cord up to 12 months post-lesion, indicating long-term microglial activation.

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NeurologyNeuroplasticityBrain Injury

Diffuse Traumatic Brain Injury Initially Attenuates and Later Expands Activation of the Rat Somatosensory Whisker Circuit Concomitant with Neuroplastic Responses

Brain Res, 2010 • April 6, 2010

This study investigates how diffuse traumatic brain injury (TBI) affects the activation and reorganization of the whisker-barrel circuit in rats. The researchers hypothesized that the extent of functi...

KEY FINDING: Whisker somatosensory regions of the cortex and thalamus maintained cellular composition as visualized by Nissl stain.

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Spinal Cord InjuryNeurologyNeuroplasticity

Cortical Overexpression of Neuronal Calcium Sensor-1 Induces Functional Plasticity in Spinal Cord Following Unilateral Pyramidal Tract Injury in Rat

PLoS Biology, 2010 • June 22, 2010

This present study demonstrates that the intracellular levels of NCS1 in adult cortical neurons can be significantly elevated by transduction with a lentiviral vector. Similarly, analogous experiments...

KEY FINDING: NCS1 overexpression in uninjured corticospinal neurons exhibited axonal sprouting across the midline into the CST-denervated side of the spinal cord following unilateral pyramidotomy.

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