Neuroplasticity Research

KEY FINDING: T12-L3 nerve transfer (NT) qualitatively improved locomotion in rats with mild thoracolumbar contusion (SCImi) and in animals with subacute moderate contusion (SCImo).

KEY FINDING: Significant differences were found in SSEP signal amplitudes when stimulating either forelimb in rats with normothermia compared to those treated with hypothermia on days 4 and 7 post-SCI.

KEY FINDING: Epidural electrical stimulation (eSCS) significantly improved motor function in rats with spinal cord injury, as measured by the BBB scale.

KEY FINDING: The study hypothesizes that early intervention (less than 60 days post-SCI) will yield the greatest improvements in walking ability and community ambulation.

KEY FINDING: Frontal delta asymmetry positively correlates with depression symptoms, while frontal alpha asymmetry negatively correlates with anxiety symptoms.

KEY FINDING: Incomplete SCI lesions are linked to increased pain sensitivity (lower PPT), suggesting altered neural processing exacerbates pain responses.

KEY FINDING: A single AIH session improved grip and pinch strength in both hands. The peak effect occurred around 3 hours after the intervention.

KEY FINDING: The long-latency TA flexion reflex was depressed in all phases of the step cycle after the combined intervention.

KEY FINDING: SCI patients showed decreased betweenness centrality in specific brain regions like the left precentral gyrus and right caudal middle frontal gyrus.

KEY FINDING: The key innovation of the proposed protocol is in the co-registration of data from three synchronised systems (high-density EEG, surface EMG and IMU) before, during and after robot-assisted gait-training.