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  4. Treatment of Acute Spinal Cord Injuries: A Survey Among Iberolatinoamerican Spine Surgeons – Part 1: Use of High-Dose Corticosteroids

Treatment of Acute Spinal Cord Injuries: A Survey Among Iberolatinoamerican Spine Surgeons – Part 1: Use of High-Dose Corticosteroids

Rev Bras Ortop, 2023 · DOI: 10.1055/s-0042-1749415 · Published: August 2, 2022

Spinal Cord InjuryPharmacologyResearch Methodology & Design

Simple Explanation

This study aimed to understand how spine surgeons in Iberolatinoamerican countries are using methylprednisolone sodium succinate (MPSS) to treat acute spinal cord injuries (ASCIs). A survey was sent to surgeons to collect information on their use of MPSS, including dosage and timing. The results showed that the use of MPSS is not widespread, and there is still controversy regarding its use, likely due to limited evidence and variations in treatment protocols.

Study Duration
Not specified
Participants
182 surgeons from Iberolatinoamerican countries
Evidence Level
Descriptive cross-sectional study as a survey

Key Findings

  • 1
    Only 37.9% of surgeons reported using corticosteroids in the initial management of ASCIs.
  • 2
    Among those who used corticosteroids, 65.2% used a high-dose bolus followed by perfusion.
  • 3
    66.7% of surgeons who used MPSS only prescribed it within 8 hours of the ASCI.

Research Summary

The study evaluated the current practice of using methylprednisolone sodium succinate (MPSS) in acute spinal cord injuries (ASCIs) among spine surgeons from Iberolatinoamerican countries. A survey was conducted among members of the Sociedad Ibero Latinoamericana de Columna (SILACO) and associated societies. The survey results indicated that MPSS use in ASCI is not widespread and the controversy regarding its use remains unresolved.

Practical Implications

Need for Standardized Protocols

The inconsistencies in MPSS prescription highlight the need for standardized treatment protocols.

Further Research

More research is needed to better uniformize the treatment of ASCI patients.

Information Dissemination

Increased information and education are necessary to standardize corticosteroid prescription.

Study Limitations

  • 1
    Relatively small number of participants from some countries
  • 2
    Information bias inherent in post-hoc studies
  • 3
    Not specified

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