Browse the latest research summaries in the field of neuroplasticity for spinal cord injury patients and caregivers.
Showing 111-120 of 153 results
Brain Sci., 2018 • December 16, 2018
The present study examined bilateral cortical organization in individuals with chronic incomplete cervical SCI and uninjured controls. Several novel findings were revealed that provide new information ...
KEY FINDING: Muscle representations in SCI are shifted medially compared to controls.
Frontiers in Neurology, 2018 • December 11, 2018
The Arm Ability Training (AAT) is specifically designed for individuals with brain injuries causing mild to moderate arm weakness and reduced dexterity, addressing sensorimotor efficiency across vario...
KEY FINDING: AAT is clinically effective in promoting dexterity recovery and reducing focal disability in stroke patients with mild to moderate arm paresis.
Respir Physiol Neurobiol, 2019 • July 1, 2019
This review discusses how local circulatory control and oxygen delivery in the spinal cord regulate different pathways to phrenic motor plasticity. Acute intermittent hypoxia (AIH) elicits distinct me...
KEY FINDING: Moderate AIH induces serotonin-dependent pLTF, which is independent of tissue hypoxia and relies on carotid body chemoreceptor activation.
Physiol Rep, 2019 • July 1, 2019
This study investigated the impact of HIIT on brain excitability, biochemical markers, and working memory in sedentary young males. Eighteen participants underwent 6 weeks of HIIT, and various measure...
KEY FINDING: HIIT significantly increased cardiorespiratory fitness (CRF) in sedentary males after 6 weeks.
J Neurol Neurosurg Psychiatry, 2012 • June 1, 2012
This study investigates the relationship between axonal integrity in the corticospinal tract (CST), spinal cord area, and cortical reorganization in subjects with traumatic spinal cord injury (SCI) us...
KEY FINDING: Diffusion tensor imaging showed significant differences in the CST of SCI subjects compared to controls in areas such as the pyramids, internal capsule, cerebral peduncle, and hand area.
Neural Plasticity, 2012 • April 10, 2012
Spinal cord injury (SCI) leads to changes in body homeostasis, affecting multiple systems. In most cases, the spinal cord isn't completely severed, leaving some nerve pathways intact. This allows the ...
KEY FINDING: BWSTT increases the MEP amplitude, changes the common drive of antagonist muscles from corticospinal inputs with subjects seated, and alters the TA MEP modulation pattern during BWS assisted stepping.
Frontiers in Physiology, 2012 • July 18, 2012
This study evaluates the effects of treadmill and cycle locomotor training on spasticity, reflex excitability, and limb use in rats with spinal cord injuries. The results indicate that both types of l...
KEY FINDING: Locomotor training, whether treadmill or bicycle, significantly reduces spasticity in rats with spinal cord injuries.
The Journal of Spinal Cord Medicine, 2014 • January 1, 2014
This study investigated the effects of functional electrical stimulation (FES) on locomotor recovery in rats with spinal cord injury (SCI). Rats were divided into FES therapy and sedentary control gro...
KEY FINDING: FES significantly improved locomotion recovery in SCI rats by day 7, as measured by BBB scores. The FES group had a significantly higher score compared to the control group.
American Journal of Respiratory and Critical Care Medicine, 2014 • January 1, 2014
This study demonstrates that ventilatory long-term facilitation can be evoked in humans with chronic, incomplete spinal cord injury. Single sessions of intermittent hypoxia induced increases in minute...
KEY FINDING: Minute ventilation significantly increased for 30 minutes after acute exposure to intermittent hypoxia in individuals with chronic spinal cord injury.
Frontiers in Neurology, 2013 • November 13, 2013
The recovery of functional movements following injury to the central nervous system (CNS) is multifaceted and is accompanied by processes occurring in the injured and non-injured hemispheres of the br...
KEY FINDING: Performing motor tasks with robot-mediated assistance can modulate neural activity compared to un-assisted or active voluntary movements in healthy subjects and stroke patients.