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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Medical Imaging Research

Browse the latest research summaries in the field of medical imaging for spinal cord injury patients and caregivers.

Showing 131-140 of 231 results

Medical ImagingOrthopedicsRehabilitation

Fracture Nonunion Treated with Low-Intensity Pulsed Ultrasound and Monitored with Ultrasonography: A Feasibility Study

BioMed Research International, 2021 • January 27, 2021

This study explored the feasibility of using low-intensity pulsed ultrasound (LIPUS) to treat fracture nonunion while monitoring for heterotopic ossification (HO) using ultrasonography. The results de...

KEY FINDING: LIPUS therapy facilitated fracture repair in a patient with nonunion, as evidenced by ultrasound and radiographic outcomes showing callus formation and a blurred fracture line.

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Spinal Cord InjuryMedical ImagingNeuroplasticity

Altered Topological Properties of Grey Matter Structural Covariance Networks in Complete Thoracic Spinal Cord Injury Patients: A Graph Theoretical Network Analysis

Neural Plasticity, 2021 • February 2, 2021

This study used VBM and graph theoretical network analyses to investigate alterations in GMV and GMV-based SCNs in complete thoracic SCI patients within one postinjury year, and partial correlation an...

KEY FINDING: SCI patients showed reduced gray matter volume in the left middle frontal cortex, right superior orbital frontal cortex (OFC), and left inferior OFC.

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NeurologyMedical Imaging

Brain fMRI during orientation selective epidural spinal cord stimulation

Scientific Reports, 2021 • March 15, 2021

This study introduces Orientation Selective Epidural Spinal Cord Stimulation (OS-ESCS) in rats and uses fMRI to monitor brain activations during stimulation of spinal segments S1 and L2. The findings ...

KEY FINDING: OS-ESCS modulates spinal-brain connectomes within the CNS, as demonstrated by brain activations during stimulation of S1 and L2 spinal segments.

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NeurologyPain ManagementMedical Imaging

LIFU Alleviates Neuropathic Pain by Improving the KCC2 Expression and Inhibiting the CaMKIV–KCC2 Pathway in the L4–L5 Section of the Spinal Cord

Neural Plasticity, 2021 • April 13, 2021

This study investigates the effect of LIFU on neuropathic pain (NP) and the expression of potassium chloride cotransporter 2 (KCC2) in the spinal cords of rats with peripheral nerve injury (PNI). The ...

KEY FINDING: LIFU stimulation alleviated mechanical allodynia in PNI model rats, as indicated by increased PWT50 values after 3 weeks of LIFU treatment compared to the LIFU− group.

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Spinal Cord InjuryMedical ImagingRehabilitation

Acute Ultrasonographic Changes in Lower Extremity Muscle Structure after Motor Complete Spinal Cord Injury

Journal of Medical Ultrasound, 2022 • July 1, 2022

This study investigated the acute ultrasonographic changes in lower extremity muscle structure in patients with motor complete spinal cord injury (SCI). The researchers found a decrease in the thickne...

KEY FINDING: There was a significant decrease in rectus femoris muscle thickness over the 4-week study period.

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Spinal Cord InjuryNeurologyMedical Imaging

Dynamics of progressive degeneration of major spinal pathways following spinal cord injury: A longitudinal study

NeuroImage: Clinical, 2023 • February 1, 2023

This study tracked the spatiotemporal dynamics of remote anterograde and retrograde spinal tract degeneration in the upper cervical cord following SCI over two years utilizing quantitative MRI. Linear...

KEY FINDING: Retrograde neurodegeneration in the CST develops over time, forming a gradient towards lower cervical levels, particularly in tetraplegics.

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Spinal Cord InjuryNeurologyMedical Imaging

Spinal cord atrophy after spinal cord injury – A systematic review and meta-analysis

NeuroImage: Clinical, 2023 • March 10, 2023

This systematic review and meta-analysis investigated spinal cord atrophy following spinal cord injury (SCI) using MRI measurements of the cervical spinal cord cross-sectional area (cSC CSA). The stud...

KEY FINDING: The meta-analysis revealed a significant reduction in cSC CSA in individuals with SCI compared to controls, with a standardized mean difference of -1.48, indicating substantial atrophy.

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Spinal Cord InjuryNeurologyMedical Imaging

Ultrasound in Traumatic Spinal Cord Injury: A Wide-Open Field

Neurosurgery, 2021 • September 1, 2021

This review explores the potential of ultrasound technology for diagnostic and therapeutic interventions in traumatic spinal cord injury (SCI). The authors discuss the fundamentals of ultrasound, incl...

KEY FINDING: Ultrasound can enable real-time In Vivo spinal cord monitoring with high spatiotemporal resolution, overcoming limitations of existing modalities.

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NeurologyMedical Imaging

MRI- and histologically derived neuroanatomical atlas of the Ambystoma mexicanum (axolotl)

Scientific Reports, 2021 • May 12, 2021

This study presents the first MRI atlas of the juvenile axolotl brain, comprising 82 and 64 regions of interest, segmented based on embryological origin and hemispheric division. The MRI atlas allows ...

KEY FINDING: The study successfully created an MRI atlas of the axolotl brain, delineating 82 regions of interest (ROIs) and a simplified version with 64 ROIs.

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Spinal Cord InjuryMedical Imaging

Novel stochastic framework for automatic segmentation of human thigh MRI volumes and its applications in spinal cord injured individuals

PLOS ONE, 2019 • May 9, 2019

This study presents a novel automatic 3-D approach for the volumetric segmentation and quantitative assessment of thigh MRI volumes in individuals with chronic SCI and non-disabled individuals. The pr...

KEY FINDING: The proposed automatic segmentation method achieved an overall accuracy of 0.93±0.06 for adipose tissue and muscle compartments segmentation based on Dice Similarity Coefficient.

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