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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Healthcare Research

Browse the latest research summaries in the field of healthcare for spinal cord injury patients and caregivers.

Showing 1-10 of 432 results

Spinal Cord InjuryHealthcare

Antimicrobial stewardship strategy implementation and impact in acute care spinal cord injury and disorder units

The Journal of Spinal Cord Medicine, 2025 • November 21, 2023

This study assessed the implementation and impact of antimicrobial stewardship (AS) strategies in spinal cord injury and disorder (SCI/D) units across Veterans Affairs (VA) facilities. The results rev...

KEY FINDING: AS strategy implementation varied across VA facilities, with pre-authorization being perceived as highly impactful (78%) and fully implemented (82%).

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Spinal Cord InjuryRegenerative MedicineHealthcare

Adverse events of cell therapy clinical trials in human chronic spinal cord injury, a systematic review and meta-analysis

Regenerative Therapy, 2024 • March 15, 2024

This study analyzed the AE of 14 types of cell therapy clinical trials in human chronic spinal cord injury and showed that in 45 studies of 76 reviewed articles, 64 types of AEs in 12 categories were ...

KEY FINDING: The most common adverse events were transient backache and meningism (90%) and cord malacia (80%).

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HealthcareNeurologyPublic Health

Quality of early stroke care and long-term mortality in patients with acute stroke: A nationwide follow-up study

European Stroke Journal, 2024 • April 8, 2024

This nationwide study examined the association between the quality of early stroke care, measured by process performance measures (PPMs), and long-term mortality in patients with acute stroke in Denma...

KEY FINDING: Fulfilment of individual process performance measures (PPMs) was associated with adjusted hazard rate ratios of death between 0.76 and 0.96.

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HealthcareOrthopedicsBiomedical

Vancomycin-encapsulated hydrogel loaded microarc-oxidized 3D-printed porous Ti6Al4V implant for infected bone defects: Reconstruction, anti-infection, and osseointegration

Bioactive Materials, 2024 • July 30, 2024

This study introduces a novel approach to treating infected bone defects using a 3D-printed porous Ti6Al4V implant modified with microarc oxidation (MAO) and loaded with a vancomycin-encapsulated hydr...

KEY FINDING: The vancomycin-encapsulated hydrogel, when loaded into the microarc-oxidized 3D-printed porous Ti6Al4V implant, exhibits effective antibacterial activity against MRSA both in vitro and in vivo.

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Spinal Cord InjuryHealthcareNeurology

The rise and fall of Queckenstedt's test between 1916 and 1970, a milestone in spinal cord diagnostics and why it matters

Eur J Neurol, 2025 • January 1, 2025

This systematic review traces the evolution of Queckenstedt's test, a routine diagnostic procedure for CSF space constriction. Clinical studies investigated its diagnostic accuracy against operative f...

KEY FINDING: Queckenstedt's test was widely adopted globally for diagnosing spinal canal obstruction, particularly spinal tumors.

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HealthcareTraumaPediatrics

Conservative treatment for traumatic atlantoaxial joint infra-anterior dislocation complicating odontoid fracture in young children: A case series

Journal of Children’s Orthopaedics, 2024 • June 13, 2024

This study presents a case series of three young children with traumatic atlantoaxial joint infra-anterior dislocation complicating odontoid fracture (ADOF) who were treated conservatively. The conser...

KEY FINDING: All three patients' C1-2 infra-anterior dislocations were successfully reduced using gentle traction methods (halo or occipital-jaw) without surgery.

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Spinal Cord InjuryHealthcareBioinformatics

Evaluating Artificial Intelligence in Spinal Cord Injury Management: A Comparative Analysis of ChatGPT-4o and Google Gemini Against American College of Surgeons Best Practices Guidelines for Spine Injury

Global Spine Journal, 2025 • January 1, 2025

This study evaluated the ability of ChatGPT-4o and Google Gemini Advanced to adhere to the 2022 American College of Surgeons (ACS) Best Practice Guidelines for spinal injury management. The AI models ...

KEY FINDING: ChatGPT-4o was correct on 73.07% of the questions, while Gemini Advanced was correct on 69.23%. Most incorrect answers were due to not providing enough information rather than giving wrong information.

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HealthcareSpinal DisordersPublic Health

Evaluation of Financial Support Workshops for Patients Under State Pension Age With Degenerative Cervical Myelopathy: Survey Study

JMIR Formative Research, 2025 • February 24, 2025

This study evaluated the effectiveness of financial support workshops for patients with DCM under state pension age in the UK. The workshops, focusing on UC and PIP, were delivered in partnership with...

KEY FINDING: Participants rated the usefulness of the UC and PIP sessions highly, with average ratings of 9.00/10 and 10/10, respectively.

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Spinal Cord InjuryHealthcareBioinformatics

A multi-analyte blood test for acute spinal cord injury

The Journal of Clinical Investigation, 2025 • January 14, 2025

This study introduces a multi-analyte blood test for acute SCI, utilizing spinal cord–derived cfDNA and plasma protein alterations to inform diagnosis and prognosis. The Spinal Cord Injury Index (SCII...

KEY FINDING: A ddPCR assay detected spinal cord–derived cfDNA in plasma of 50 patients with acute SCI (AUC: 0.89, 95% CI 0.83–0.95, P < 0.0001).

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HealthcareTraumaPublic Health

Risk factors and economic impact of long-term nursing care after major trauma

Front. Public Health, 2025 • March 18, 2025

This study examined risk factors and economic impacts of long-term nursing care (LTC) after major trauma in Taiwan using National Health Insurance Research Database data from 2003-2007 with a 10-year ...

KEY FINDING: Age, comorbidities, spinal cord injury, prolonged mechanical ventilation, prolonged ICU stay, and prolonged hospital stay are independent risk factors for needing long-term nursing care (LTC).

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