Spinal Cord Injury ResearchAccessible to Everyone
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MyoGestic: EMG interfacing framework for decoding multiple spared motor dimensions in individuals with neural lesions
Science Advances, 2025 • April 9, 2025
The study introduces MyoGestic, a neural interface system that includes a 32-channel monopolar EMG bracelet and an open-source software framework designed for rapid experimentation and adaptation to participant-specific needs. MyoGestic enables the r...
KEY FINDING: The study successfully decoded motor intent in real time from participants with SCI, spinal stroke, and amputations, achieving multiple controllable motor dimensions within minutes.
Human Schwann Cell-Derived Extracellular Vesicle Isolation, Bioactivity Assessment, and Omics Characterization
International Journal of Nanomedicine, 2025 • April 4, 2025
The study establishes a robust framework for SCEV isolation and their comprehensive characterization, which is consistent with their therapeutic potential in neurological applications. This work provides a valuable proteomic, lipidomic, and miRNA dat...
KEY FINDING: The study established a reliable method for isolating SCEVs with consistent molecular profiles.
An engineering-reinforced extracellular vesicle–integrated hydrogel with an ROS-responsive release pattern mitigates spinal cord injury
Sci. Adv., 2025 • April 2, 2025
This study engineered mesenchymal stem cell-derived extracellular vesicles (EVs) to enhance their therapeutic efficacy for spinal cord injury (SCI) treatment. The EVs were reinforced with pro-angiogenic, neurotrophic, and anti-inflammatory effects an...
KEY FINDING: The study successfully created a hydrogel that releases EVs in response to ROS, allowing for on-demand regulation of SCI treatment.
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