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  4. Verification of a system utilizing heartbeat‑induced acoustic pulse waves for estimating the time at which bladder urine increases to a level requiring drainage among individuals with spinal cord injury

Verification of a system utilizing heartbeat‑induced acoustic pulse waves for estimating the time at which bladder urine increases to a level requiring drainage among individuals with spinal cord injury

BioMedical Engineering OnLine, 2024 · DOI: https://doi.org/10.1186/s12938-024-01317-w · Published: November 16, 2024

Spinal Cord InjuryUrologyNeurology

Simple Explanation

Spinal cord injury (SCI) can disrupt urinary sensation, leading to difficulties with urination. The study explores using heartbeat-induced acoustic pulse waves (HAPWs) to estimate when individuals with SCI need to drain their bladder, preventing complications like autonomic dysreflexia. The system monitors autonomic nervous activity through HAPWs to detect when urine volume increases to a level requiring drainage. It adapts an algorithm (ATUI) previously tested on healthy individuals, modifying thresholds to suit SCI patients. The adapted algorithm showed promising results in detecting the need for urinary drainage in SCI patients without missing urination times or identifying false alarms, suggesting a practical solution for managing urinary health and preventing related complications.

Study Duration
Not specified
Participants
10 males with spinal cord injury
Evidence Level
Not specified

Key Findings

  • 1
    The original algorithm, developed using data from healthy participants, showed an F-score of 0.70 when applied to individuals with SCI, indicating moderate accuracy in detecting the need for urinary drainage.
  • 2
    Adapting the algorithm by modifying three thresholds significantly improved its accuracy, achieving an F-score of 1.00. This suggests the potential for personalized adjustments to enhance the system's performance for SCI patients.
  • 3
    The study found that the heart rate variability (HRV) in ultralow/very low frequency bands is important for autonomic nervous activity associated with increased urine in the bladder.

Research Summary

This study aimed to verify and adapt an algorithm (ATUI) that uses heartbeat-induced acoustic pulse waves (HAPWs) to estimate the time at which individuals with spinal cord injury (SCI) need to drain their bladder, addressing the loss of urinary sensation and related complications. The original ATUI, developed with data from healthy participants, was tested on ten SCI patients. After identifying limitations, the algorithm was adapted by modifying three thresholds, which significantly improved its accuracy in detecting the need for urinary drainage. The adapted ATUI achieved an F-score of 1.00, demonstrating its potential as a practical solution for managing urinary health in individuals with SCI. The study also highlighted the importance of heart rate variability in ultralow/very low frequency bands in detecting increased urine in the bladder.

Practical Implications

Improved Urinary Management

The system can provide a non-invasive method for individuals with SCI to manage their urinary drainage, reducing the risk of complications like autonomic dysreflexia.

Enhanced Quality of Life

By accurately detecting the need for urinary drainage, the system can reduce barriers to social participation and improve the overall quality of life for individuals with SCI.

Potential for AI Integration

Future AI-based mechanisms can dynamically adjust thresholds to improve the accuracy of the ATUI, enabling personalized and more reliable urinary management.

Study Limitations

  • 1
    The study had a limited number of training data sets (12 sets) from ten participants with SCI, potentially affecting the reliability of the findings and increasing the risk of overfitting.
  • 2
    The intermittent measurement of intravesical urine volume reduced the temporal accuracy of the algorithm output examination.
  • 3
    The study's reliance on phenomenological data (HRV in ultralow/very low frequency bands) requires further knowledge and validation of these data to strengthen the estimation system.

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