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  4. Spinal cord stimulation and rehabilitation in an individual with chronic complete L1 paraplegia due to a conus medullaris injury: motor and functional outcomes at 18 months

Spinal cord stimulation and rehabilitation in an individual with chronic complete L1 paraplegia due to a conus medullaris injury: motor and functional outcomes at 18 months

Spinal Cord Series and Cases, 2020 · DOI: https://doi.org/10.1038/s41394-020-00345-7 · Published: September 21, 2020

Spinal Cord InjuryPain ManagementRehabilitation

Simple Explanation

This case report explores the use of spinal cord stimulation (SCS) combined with physical therapy to improve motor function and quality of life in a patient with complete paraplegia. The patient, who had a spinal cord injury at the L1 level resulting in complete paralysis and neuropathic pain, underwent SCS implantation at the conus medullaris and participated in an intensive physical therapy program. While the patient did not regain full motor function, improvements were observed in the zones of partial preservation, resting EMG amplitudes, and overall quality of life, suggesting potential for neuroplasticity even in this patient population.

Study Duration
18 months
Participants
One 48-year-old male with chronic complete L1 paraplegia
Evidence Level
Level 4: Case Report

Key Findings

  • 1
    Motor ZPPs advanced from L1 to L5 on the left and from L1 to L3 on the right after 18 months of SCS and physical therapy.
  • 2
    Qualitative increases in lower extremity resting state EMG amplitudes were noted, although there was no consistent evidence of voluntary EMG or rhythmic locomotive leg movements.
  • 3
    Three validated functional and quality of life (QoL) surveys demonstrated substantial improvements after 18 months of motor rehabilitation with EES.

Research Summary

This case report details the effects of spinal cord stimulation (SCS) and rehabilitation on a 48-year-old male with chronic complete L1 paraplegia due to a conus medullaris injury. The patient underwent SCS implantation and an intensive physical therapy regimen. Although intraoperative EMG did not show muscle activation with stimulation, postoperative assessments revealed advancements in motor zones of partial preservation. Functional and quality of life surveys showed substantial improvements, suggesting potential for neuroplasticity despite the severity and location of the injury.

Practical Implications

Potential for Neuroplasticity

Even in patients with complete SCI and injuries to the conus medullaris, spinal cord stimulation combined with rehabilitation may induce neuroplastic changes and improve quality of life.

Personalized Therapy

The study highlights the importance of tailoring therapeutic approaches to individual patient characteristics, considering the specific injury pattern and potential confounding factors.

Further Research

Further investigation is needed to optimize stimulation parameters and rehabilitation protocols to maximize motor recovery and functional outcomes in patients with similar injuries.

Study Limitations

  • 1
    Single case report limits generalizability
  • 2
    Confounding factors such as mixed injury patterns and neuropathic pain
  • 3
    Lack of separation between sensory, motor, or psychological impacts of the therapy

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