Spinal Cord Research Help
AboutCategoriesLatest ResearchContact
Subscribe
Spinal Cord Research Help

Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

Quick Links

  • Home
  • About
  • Categories
  • Latest Research
  • Disclaimer

Contact

  • Contact Us
© 2025 Spinal Cord Research Help

All rights reserved.

  1. Home
  2. Research
  3. Spinal Cord Injury
  4. Spinal cord injured women’s treatment of breast carcinoma: alert to complications

Spinal cord injured women’s treatment of breast carcinoma: alert to complications

Spinal Cord Series and Cases, 2018 · DOI: https://doi.org/10.1038/s41394-018-0079-2 · Published: April 15, 2018

Spinal Cord InjuryOncologyRehabilitation

Simple Explanation

Women with spinal cord injuries who develop breast cancer face unique challenges due to decreased mobility and potential complications from cancer treatment. These complications can include issues like reflexive diaphoresis, urinary tract infections, and pressure sores, requiring a multidisciplinary approach to care. Decreased mobility increases risks of venous thromboembolism, falls, pressure injuries, and infections. Pressure injuries are a potentially deadly and costly complication of spinal cord injuries, with costs in the United States estimated to be up to $11 billion annually. This case highlights the importance of considering the unique pathophysiologic changes associated with SCI when treating breast cancer in women with SCI to prevent complications and improve outcomes.

Study Duration
Not specified
Participants
One 54-year-old woman with T6 AIS A traumatic SCI
Evidence Level
Case Report

Key Findings

  • 1
    Chemotherapy in women with SCI can lead to complications such as reflexive diaphoresis, urinary tract infection, leukopenia, anemia, dehydration, and weakness, contributing to pressure sore development.
  • 2
    SCI-related pathophysiologic changes, including impaired vasomotor pathways and decreased adrenergic receptor density, can hinder the inflammatory response and wound healing.
  • 3
    Previous pressure injuries increase the risk of recurrence due to poorer collagen quality and incomplete healing.

Research Summary

This case report highlights the unique challenges faced by women with spinal cord injuries (SCI) who develop breast cancer, focusing on a 54-year-old woman with a history of traumatic paraplegia who experienced several complications during chemotherapy, including a severe pressure sore. The discussion emphasizes the importance of a multidisciplinary approach that considers the pathophysiologic changes associated with SCI to prevent complications such as pressure injuries, which can significantly impact healthcare utilization, costs, and quality of life. The authors advocate for increased awareness among healthcare providers regarding the specific needs of this population and the potential adverse effects of oncologic treatments in persons with SCI, stressing the role of physiatrists in managing medical complications and improving outcomes.

Practical Implications

Multidisciplinary Care

Emphasizes the need for a comprehensive rehabilitation team including wound care, therapy, and dietary support for SCI patients undergoing cancer treatment.

Early Intervention

Highlights the importance of early evaluation and management of potential complications like pressure injuries to prevent progression and improve healing outcomes.

Personalized Treatment

Advocates for tailoring treatment plans to address the unique pathophysiologic changes and comorbidities associated with SCI to minimize risks and optimize quality of life.

Study Limitations

  • 1
    Single case study limits generalizability.
  • 2
    Paucity of literature on this specific patient population.
  • 3
    Not specified

Your Feedback

Was this summary helpful?

Back to Spinal Cord Injury