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  4. Spinal arachnoiditis leading to recurrent reversible myelopathy: A case report

Spinal arachnoiditis leading to recurrent reversible myelopathy: A case report

The Journal of Spinal Cord Medicine, 2022 · DOI: 10.1080/10790268.2020.1830250 · Published: May 1, 2022

Spinal Cord InjuryNeurologyResearch Methodology & Design

Simple Explanation

Arachnoiditis is a rare condition where the membrane surrounding the spinal cord becomes inflamed, leading to fibrosis and adhesions. This can cause pain, spasms, sensorimotor changes, and sometimes urinary incontinence. This case report describes a patient with a history of a gunshot wound who developed spinal arachnoiditis. The unique aspect of this case is the recurrent and reversible nature of the patient's myelopathy symptoms. The patient experienced temporary improvements in symptoms after a lumbar puncture and after a fall, suggesting pressure changes within the arachnoiditis-associated loculations may have caused the improvements. Surgical intervention ultimately provided lasting relief.

Study Duration
Not specified
Participants
One 65-year-old male
Evidence Level
Level 4: Case Report

Key Findings

  • 1
    The patient experienced recurrent and sudden reversibility of myelopathy symptoms associated with spinal arachnoiditis, which is an unusual presentation of the condition.
  • 2
    Temporary symptom resolution occurred after a lumbar puncture and a fall, suggesting that pressure changes within the spinal fluid may have influenced nerve function.
  • 3
    Surgical intervention involving lysis of adhesions and resection of a cystic lesion resulted in persistent symptom improvement.

Research Summary

This case report describes a patient with spinal arachnoiditis resulting from a remote gunshot wound, who experienced recurrent reversible myelopathy. The patient's symptoms temporarily improved after a lumbar puncture and a fall, indicating a dynamic process influenced by spinal fluid pressure. Surgical intervention led to lasting symptom improvement, highlighting the potential benefit of surgery for arachnoiditis patients with waxing and waning symptoms.

Practical Implications

Diagnostic consideration

Patients with suspected arachnoiditis who have unexpected transient improvements in myelopathic symptoms should be evaluated for surgically remediable lesions.

Treatment Strategy

Surgical intervention, including lysis of adhesions and resection of cystic lesions, may be beneficial for arachnoiditis patients with recurrent, reversible symptoms.

Etiology Awareness

Remote traumatic injuries, such as gunshot wounds, should be considered as potential causes of spinal arachnoiditis, along with other etiologies like myelographic dye irritation.

Study Limitations

  • 1
    Single case report limits generalizability.
  • 2
    Uncertainty regarding the specific contribution of chemical versus traumatic etiology.
  • 3
    Lack of animal models to support pathophysiologic hypothesis.

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