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  4. Short-Term Effect of Percutaneous Bipolar Continuous Radiofrequency on Sacral Nerves in Patients Treated for Neurogenic Detrusor Overactivity After Spinal Cord Injury: A Randomized Controlled Feasibility Study

Short-Term Effect of Percutaneous Bipolar Continuous Radiofrequency on Sacral Nerves in Patients Treated for Neurogenic Detrusor Overactivity After Spinal Cord Injury: A Randomized Controlled Feasibility Study

Ann Rehabil Med, 2015 · DOI: 10.5535/arm.2015.39.5.718 · Published: October 1, 2015

Spinal Cord InjuryUrologyRehabilitation

Simple Explanation

This study investigates the use of radiofrequency ablation on sacral nerves to treat overactive bladder in patients with spinal cord injuries. The study involved applying percutaneous bipolar continuous radiofrequency (CRF) to the S2 and S3 nerves in the intervention group. The results showed improvements in urinary incontinence and quality of life in the intervention group compared to the control group.

Study Duration
3 months
Participants
10 patients with spinal cord injury and neurogenic detrusor overactivity
Evidence Level
Level 1, Randomized Controlled Feasibility Study

Key Findings

  • 1
    Percutaneous bipolar CRF applied to sacral nerves might be an effective therapy for neurogenic overactive bladder.
  • 2
    The intervention group showed improvements in daily mean frequency and volume of urinary incontinence and in ICIQ and IQOL scores compared with the control group with respect to time.
  • 3
    Significant intergroup differences were found in pre/post volume differences at maximal detrusor pressures during filling and in reflex detrusor volumes.

Research Summary

This study investigated the short-term effects of bipolar radiofrequency (RF) ablation of sacral nerves for treating neurogenic detrusor overactivity in spinal cord injury patients. The intervention group received percutaneous bipolar continuous RF on the S2 and S3 spinal nerves, while the control group received conventional medical treatment. The study concluded that percutaneous bipolar CRF applied to sacral nerves could be an effective therapy for neurogenic overactive bladder, reducing urinary incontinence and improving quality of life.

Practical Implications

Clinical Practice

Percutaneous bipolar CRF can be considered as a treatment option for neurogenic overactive bladder in spinal cord injury patients.

Quality of Life Improvement

This therapy has the potential to reduce urinary incontinence and improve the overall quality of life for affected individuals.

Cost-Effective Alternative

Bipolar CRF is a cost-effective alternative to more invasive procedures like neuromodulation therapy.

Study Limitations

  • 1
    The major limitation of this study is the small number of subjects enrolled.
  • 2
    Furthermore, we evaluated results at only three months after intervention.
  • 3
    Additional larger-scale, longer follow-up studies be conducted.

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