Research on stem cell therapy for spinal cord injury: a bibliometric and visual analysis from 2018–2023

Frontiers in Genetics, 2024 · DOI: 10.3389/fgene.2024.1327216 · Published: February 6, 2024

Spinal Cord Injury Regenerative Medicine Research Methodology & Design

Simple Explanation

This study analyzes research trends in stem cell therapy for spinal cord injury (SCI) from 2018 to mid-2023 using bibliometric methods. It aims to understand the field's progress and identify emerging research topics. The study uses tools like CiteSpace and VOSviewer to analyze publications, identify key contributors (countries, institutions, authors), and map collaborative networks in SCI stem cell research. The findings highlight research hotspots like hereditary paraplegia, reactive astrocytes, and tissue engineering. The study suggests stem cell transplantation and exosome therapy are potential future research areas.

Study Duration

5.5 Years

Participants

2,150 valid papers

Evidence Level

Not specified

Key Findings

1
The number of publications on stem cell therapy for SCI has been steadily increasing from 2018 to 2023, indicating growing interest in the field.
2
China is the country with the greatest number of publications and citations, while the Chinese Academy of Sciences is the leading institution.
3
High-frequency keyword clusters include hereditary paraplegia, reactive astrocytes, and tissue engineering, reflecting key research areas.

Research Summary

This study conducted a bibliometric analysis of stem cell therapy for spinal cord injury research from 2018 to 2023, utilizing databases like Web of Science and tools like CiteSpace and VOSviewer. The analysis identified key trends, active researchers, leading institutions, and prominent countries in the field, highlighting collaborative networks and research hotspots. The findings suggest that stem cell transplantation, exosome therapy, and tissue engineering are potential future research areas, providing a foundation for future research and clinical efforts in spinal cord injury treatment.

Practical Implications

Future Research Focus

Highlights stem cell transplantation and exosome therapy as potential areas for future research in spinal cord injury treatment.

Collaboration Enhancement

Encourages stronger collaboration and communication between different research institutions and teams worldwide.

Clinical Translation

Supports the development of new therapeutic approaches through stem cell transplantation and exosome stabilization for clinical applications.

Study Limitations

1
The study may not have captured every document entirely pertinent to the subject.
2
Self-reference bias was not taken into account.
3
The search criteria might have specified the studies' topics.

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