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  4. Preoperative Embolization of Metastatic Spinal Cord Compression With N-Butyl Cyanoacrylate: Safety and Effectiveness in Limiting Blood Loss

Preoperative Embolization of Metastatic Spinal Cord Compression With N-Butyl Cyanoacrylate: Safety and Effectiveness in Limiting Blood Loss

J Vasc Interv Radiol, 2023 · DOI: 10.1016/j.jvir.2023.01.009 · Published: April 1, 2023

Spinal Cord InjuryOncology

Simple Explanation

This study investigates using a glue-like substance, n-BCA, to block blood flow to spinal tumors before surgery. The goal is to reduce blood loss during surgery for metastatic spinal cord compression (MSCC). Researchers reviewed records of 20 patients who underwent this procedure to assess its safety and effectiveness.

Study Duration
2017 to 2022
Participants
20 patients (11 men, 9 women)
Evidence Level
Retrospective study

Key Findings

  • 1
    Preoperative embolization with n-BCA is a safe procedure for MSCC.
  • 2
    The procedure effectively reduces tumor vascularity before surgery.
  • 3
    Surgery can be performed with acceptable blood loss after embolization with n-BCA.

Research Summary

This retrospective study evaluated the safety and efficacy of preoperative embolization using n-BCA for patients with metastatic spinal cord compression. Only one patient experienced severe adverse events after embolization. Embolization with n-BCA is effective and allows for surgery performance with acceptable blood loss.

Practical Implications

Reduced Blood Loss

Preoperative embolization with n-BCA can significantly reduce intraoperative blood loss in patients undergoing surgery for MSCC.

Safe Procedure

The study suggests that n-BCA embolization is a relatively safe procedure with a low risk of severe adverse events.

Effective Tumor Devacularization

n-BCA embolization is effective in reducing tumor vascularity, facilitating easier and safer surgical resection.

Study Limitations

  • 1
    Retrospective design
  • 2
    Low number of patients
  • 3
    No comparison with another intervention or embolic agent

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