Percutaneous laser disc decompression combined with secretome of umbilical cord-derived mesenchymal stem cells in a patient with spinal cord injury: A case report

International Journal of Surgery Case Reports, 2024 · DOI: https://doi.org/10.1016/j.ijscr.2023.109219 · Published: January 2, 2024

Spinal Cord Injury Regenerative Medicine Pain Management

Simple Explanation

Spinal cord injuries can greatly affect a person's life. Common treatments involve surgery, but a less invasive option is Percutaneous Laser Disc Decompression (PLDD). PLDD offers advantages such as being less invasive, requiring shorter hospital stays, and allowing for quicker recovery. This case study looks at using PLDD with stem cell secretomes to help older patients with spinal cord injuries regenerate and improve their spinal health.

Study Duration

1 year

Participants

A 64-year-old male

Evidence Level

Case Report

Key Findings

1
PLDD significantly reduced the patient's discomfort within 24 hours.
2
UC-MSC secretomes enhanced the regenerative process and increased bone mineral density over three to six months, indicating spine regeneration.
3
The patient experienced improved motor strength, enhanced postural stability, and could walk without assistance after one year.

Research Summary

This case report describes the successful treatment of a 64-year-old male with a spinal cord injury using percutaneous laser disc decompression (PLDD) combined with umbilical cord-derived mesenchymal stem cell (UC-MSC) secretomes. The patient, who presented with bilateral limb weakness and back pain, showed significant improvement in pain levels, motor strength, and postural stability following the combined treatment. The study suggests that this approach may be a viable option for older individuals at higher surgical risks, offering both immediate symptom relief and long-term spinal quality improvement.

Practical Implications

Less Invasive Treatment Option

PLDD combined with UC-MSC secretomes offers a less invasive alternative to traditional surgery for spinal cord injuries, reducing risks and recovery time.

Enhanced Spinal Regeneration

The use of UC-MSC secretomes promotes bone regeneration and increases bone mineral density, leading to long-term spinal quality improvement.

Improved Patient Outcomes

Patients experience significant pain reduction, improved motor strength, and enhanced postural stability, allowing for increased independence and quality of life.

Percutaneous laser disc decompression combined with secretome of umbilical cord-derived mesenchymal stem cells in a patient with spinal cord injury: A case report

Simple Explanation

Key Findings

Research Summary

Practical Implications

Less Invasive Treatment Option

Enhanced Spinal Regeneration

Improved Patient Outcomes

Study Limitations

Your Feedback

Was this summary helpful?

Percutaneous laser disc decompression combined with secretome of umbilical cord-derived mesenchymal stem cells in a patient with spinal cord injury: A case report

Simple Explanation

Key Findings

Research Summary

Practical Implications

Less Invasive Treatment Option

Enhanced Spinal Regeneration

Improved Patient Outcomes

Study Limitations

Your Feedback

Was this summary helpful?