Neuro-Urology and Biobanking: An Integrated Approach for Advancing Research and Improving Patient Care

Biobanks collect and store biological samples like urine, blood, tissue, and DNA to study the molecular mechanisms behind neuro-urological disorders. This helps researchers identify genetic variations and other factors associated with neurogenic lower urinary tract dysfunction, common in diseases like Alzheimer’s and Parkinson’s. High-tech methods such as next-generation sequencing allow for in-depth exploration of these conditions. Biomarkers developed from this research aid in early detection, accurate diagnosis, and effective monitoring of neuro-urological conditions, ultimately improving patient care and treatment. The integration of neuro-urology and biobanking offers a synergistic approach, translating biobanking practices into molecular research to improve patient outcomes. This review emphasizes the translation of biobanking approaches in molecular research in neuro-urology.

• 1
  Biobanking facilitates the identification of genetic variations, epigenetic modifications, and gene expression patterns associated with neurogenic lower urinary tract dysfunction, which are symptoms of neurological diseases.
• 2
  High-throughput technologies enable researchers to explore the molecular landscape of neuro-urological conditions in an unprecedented manner, leading to specific and reliable biomarkers.
• 3
  Standardization and quality assurance in sample collection are crucial, and challenges that may compromise sample quality must be addressed to ensure the subsequent utilization of the samples.