Methodology of Systematic Reviews and Recommendations

Journal of Neurotrauma, 2011 · DOI: 10.1089=neu.2009.1146 · Published: August 1, 2011

Spinal Cord Injury Research Methodology & Design

Simple Explanation

This paper outlines the methodology used for conducting systematic reviews of the literature on spinal cord injury (SCI) research. The goal was to develop evidence-based recommendations to translate science into clinical practice and identify new research directions. A multidisciplinary panel of experts was assembled to formulate questions and review the literature. The process involved a comprehensive search of multiple databases, independent review of articles, data extraction, and assessment of evidence level and methodological quality. Recommendations were generated based on the evidence using Delphi methods to achieve consensus among the expert panel, enhancing the validity of the guidelines.

Study Duration

Not specified

Participants

Multidisciplinary group of experts

Evidence Level

Not specified

Key Findings

1
The methodology included a comprehensive literature search across multiple databases (MEDLINE, CINAHL, EMBASE, Cochrane) from 1966 to April 2009.
2
A common search strategy for acute SCI was developed and tailored for each research question, ensuring consistency across reviews.
3
Recommendations were established based on systematic reviews, author statements, and Delphi process with levels of agreement reported.

Research Summary

The paper describes the methodology used to conduct systematic reviews on 12 key topics related to acute traumatic spinal cord injury (SCI). The process involved assembling an expert panel, formulating specific research questions, performing a comprehensive literature search, and extracting data for analysis. Recommendations were generated using Delphi methods to achieve consensus among experts, enhancing the validity and reliability of the findings.

Practical Implications

Clinical Practice Guidelines

Provides a structured approach for developing evidence-based guidelines in SCI management.

Future Research

Identifies knowledge gaps and areas needing further research in acute SCI treatment.

Methodological Rigor

Emphasizes the importance of systematic reviews and Delphi methods for establishing valid recommendations.

Study Limitations

1
Primary search strategy limited to English language publications.
2
Potential for bias in study selection and data abstraction despite independent reviews.
3
Reliance on expert opinion and consensus in the Delphi process.

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