Hyperbaric oxygen therapy combined with Schwann cell transplantation promotes spinal cord injury recovery

This study investigates whether combining Schwann cell transplantation with hyperbaric oxygen therapy leads to better recovery from spinal cord injury compared to using either treatment alone. Rat models of spinal cord contusion injury were treated with Schwann cell transplantation, hyperbaric oxygen therapy, or a combination of both. The combined treatment showed greater improvement in hindlimb motor function and nerve regeneration compared to the individual treatments.

• 1
  The combined treatment of Schwann cell transplantation and hyperbaric oxygen therapy was more effective in improving hindlimb motor function than either treatment alone.
• 2
  Injured spinal tissue in the combination group showed a greater number of neurite-like structures.
• 3
  Somatosensory and motor evoked potential latencies were notably shorter, and their amplitudes greater, after combination therapy than after monotherapy.