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  4. Electrical stimulation of the urethra evokes bladder contractions and emptying in spinal cord injury men: Case studies

Electrical stimulation of the urethra evokes bladder contractions and emptying in spinal cord injury men: Case studies

The Journal of Spinal Cord Medicine, 2011 · DOI: 10.1179/2045772311Y.0000000012 · Published: January 1, 2011

Spinal Cord InjuryUrologyNeurology

Simple Explanation

This study explores whether electrical stimulation of the urethra can cause the bladder to contract and empty in men with spinal cord injuries. The goal is to develop a device that uses electrical stimulation to restore bladder control. Two men with spinal cord injuries participated in the study. A catheter with electrodes was placed in their urethra, and electrical stimulation was applied to see if it could trigger bladder contractions and emptying. The results showed that electrical stimulation of the urethra did evoke bladder contractions and emptying in both subjects, suggesting this could be a potential method for bladder management in SCI patients.

Study Duration
Not specified
Participants
Two men with spinal cord injury
Evidence Level
Level 4, Case Studies

Key Findings

  • 1
    Electrical stimulation of the prostatic urethra evoked bladder contractions that emptied the bladder in both subjects.
  • 2
    In the first subject, stimulation (9–12 mA, 20 Hz) emptied 64–75%, leaving post-void residual volumes (PVRs) of 41–20 ml.
  • 3
    In the second subject, stimulation (20 mA, 20 Hz) emptied 68–77%, leaving PVRs of 56–45 ml.

Research Summary

The study investigated the feasibility of using electrical stimulation of the urethra to evoke bladder emptying in men with spinal cord injury (SCI). Two participants with SCI underwent urodynamic testing with urethral electrical stimulation. The stimulation successfully evoked bladder contractions and emptying in both subjects, reducing post-void residual volumes. The findings suggest that urethral stimulation may offer a potential method for restoring bladder function in individuals with SCI, by selectively activating inhibitory or excitatory bladder reflexes.

Practical Implications

Bladder control restoration

Electrical stimulation of the urethra could potentially be developed into an implantable device to restore bladder function in individuals with spinal cord injuries.

Alternative to catheterization

Urethral stimulation may provide an alternative method to intermittent catheterization for bladder management in SCI patients.

Selective bladder control

By adjusting stimulation parameters, it may be possible to selectively inhibit or excite the bladder, allowing for both continence and micturition.

Study Limitations

  • 1
    Small sample size (two participants) limits generalizability.
  • 2
    Electromyogram activity was not recorded, limiting insight into detrusor-sphincter dyssynergia.
  • 3
    Long-term efficacy and safety of urethral stimulation were not evaluated.

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