Spinal Cord Research Help
AboutCategoriesLatest ResearchContact
Subscribe
Spinal Cord Research Help

Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

Quick Links

  • Home
  • About
  • Categories
  • Latest Research
  • Disclaimer

Contact

  • Contact Us
© 2025 Spinal Cord Research Help

All rights reserved.

  1. Home
  2. Research
  3. Spinal Cord Injury
  4. Effect of epidural spinal cord stimulation on female sexual function after spinal cord injury

Effect of epidural spinal cord stimulation on female sexual function after spinal cord injury

Frontiers in Neuroscience, 2023 · DOI: 10.3389/fnins.2023.1155796 · Published: April 5, 2023

Spinal Cord InjuryUrologyNeurology

Simple Explanation

Sexual dysfunction is a common issue for women after spinal cord injury (SCI). This study looked at whether epidural spinal cord stimulation (ESCS) could help improve sexual function and reduce distress in women with SCI. Three women with long-term, complete SCI received ESCS for 13 months. They completed questionnaires about their sexual function and distress each month. The study found that ESCS may be a promising treatment for sexual dysfunction and distress in women with severe SCI. More research is needed to confirm these findings.

Study Duration
13 months
Participants
Three females with chronic, thoracic, sensorimotor complete SCI
Evidence Level
Level 4; Case Series

Key Findings

  • 1
    There was a 3.2-point (13.2%) mean increase in total FSFI from baseline to post-intervention, with improvements in desire, arousal, orgasm and satisfaction.
  • 2
    Sexual distress was reduced by 55%, with a mean decrease of 12 points (55.4%) from baseline to post-intervention.
  • 3
    There was a clinically meaningful change of 14 points in the International Standards for Neurological Classification of Spinal Cord Injury total sensory score from baseline to post-intervention.

Research Summary

This study investigated the effect of epidural spinal cord stimulation (ESCS) on sexual function and distress in women with spinal cord injury (SCI). Three females with chronic, complete SCI received daily ESCS for 13 months. Questionnaires were used to assess sexual function and distress monthly. The study found improvements in sexual function and reduced distress with ESCS, suggesting it could be a promising treatment for women with severe SCI.

Practical Implications

Therapeutic intervention development

Developing therapeutic interventions for sexual function is one of the most meaningful recovery targets for people with SCI.

Future Research

Additional large-scale investigations are needed to understand the long-term safety and feasibility of ESCS as a viable therapy for sexual dysfunction.

Paired intervention strategies

Develop paired intervention strategies that include the addition of cognitive training such as mindfulness, which has been shown to decrease sexual distress in the female neurogenic population

Study Limitations

  • 1
    Small sample size
  • 2
    Restrictive for statistical power
  • 3
    Limits the generalizability of these findings to the larger SCI population

Your Feedback

Was this summary helpful?

Back to Spinal Cord Injury