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  4. Depression trajectories during the first year after spinal cord injury

Depression trajectories during the first year after spinal cord injury

Arch Phys Med Rehabil, 2016 · DOI: 10.1016/j.apmr.2015.10.083 · Published: February 1, 2016

Spinal Cord InjuryMental HealthRehabilitation

Simple Explanation

This study looked at how depression changes in people during the first year after a spinal cord injury (SCI). The researchers wanted to find out if there were different patterns of depression and what factors might predict these patterns. The study found three main groups: those with consistently low depression, those with mild to moderate depression, and those with persistent moderate to severe depression. Factors like past mental health issues, pain, quality of life, and grief were linked to which group a person belonged to. The findings suggest that many people with SCI don't experience significant depression, while a smaller group has ongoing or worsening depression that often relates to pre-existing mental health problems. This information could help doctors identify and treat people at risk for depression after SCI.

Study Duration
1 year
Participants
141 patients with acute SCI
Evidence Level
Cohort study

Key Findings

  • 1
    Three distinct depression trajectories were identified: stable low depression (63.8%), mild to moderate depression (29.1%), and persistent moderate to severe depression (7.1%).
  • 2
    Pre-injury mental health history was a significant predictor of depression trajectory, with a history of depression being most prevalent in the persistent moderate to severe depression group (89%).
  • 3
    Baseline pain, quality of life, and grief levels were also predictive of class membership, with the persistent moderate to severe depression group reporting lower quality of life and higher pain and grief.

Research Summary

The study aimed to identify depression trajectories during the first year after SCI and to determine baseline predictors of these trajectories. A cohort of 141 participants was assessed at 3, 6, 9, and 12 months after SCI using the PHQ-9. Latent class growth analysis revealed three distinct trajectories: stable low depression, mild to moderate depression, and persistent moderate to severe depression. The majority of participants (63.8%) were in the stable low depression group. Pre-injury mental health history, baseline pain, quality of life, and grief predicted class membership. The findings suggest that persistent depression after SCI often represents a continuation or relapse of pre-injury depression.

Practical Implications

Improved Identification of At-Risk Subgroups

The identification of distinct depression trajectories can help clinicians identify individuals at higher risk for poor mental health outcomes after SCI.

Targeted Intervention Development

Understanding the predictors of different depression trajectories can inform the development of targeted interventions tailored to the specific needs of homogenous subgroups.

Patient Education and Treatment Planning

Clinicians can use the trajectory information to educate patients about the potential course of depression after SCI and to develop personalized treatment plans.

Study Limitations

  • 1
    Single site study with a modest sample size and limited gender or racial and ethnic diversity.
  • 2
    Narrow focus on depressive symptoms, without examining other co-occurring mental health conditions.
  • 3
    Lack of information on outpatient depression treatments that may have influenced the course of depressive symptoms.

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