Conditional neuromodulation of neurogenic detrusor overactivity using transrectal stimulation in patients with spinal cord injury: A proof of principle study

This study tested a new device for controlling bladder problems (neurogenic detrusor over-activity) in men with spinal cord injuries. The device uses electrical stimulation through the anal canal to calm the bladder when it becomes overactive, as detected by anal sphincter muscle activity. The results showed the device increased bladder capacity and reduced bladder pressure in most participants, suggesting it could be a helpful treatment.

• 1
  Conditional neuromodulation significantly increased bladder capacity in six male subjects with spinal cord injury.
• 2
  Conditional neuromodulation significantly reduced maximum detrusor pressure.
• 3
  EAS activity was a reliable surrogate for detection of NDO.