Clinical Significance of Urodynamic Study Parameters in Maintenance of Renal Function in Spinal Cord Injury Patients

Neurogenic bladder is a frequent issue for individuals with spinal cord injuries. It can lead to kidney problems, a major cause of death in this group in the past. Therefore, a key goal is to prevent urinary tract complications and maintain kidney health. Urodynamic studies (UDS) are the best way to assess lower urinary tract function. Regular UDS follow-up is crucial for maintaining renal function in spinal cord injury patients. This study analyzes the link between UDS measurements and kidney function in SCI patients with neurogenic detrusor overactivity. Instead of relying on morphological changes, this study analyzes the association of UDS parameters with renal function evaluations.

• 1
  Cystometric capacity was significantly larger and maximal detrusor pressure was significantly lower on follow-up, likely due to treatment.
• 2
  Univariate analysis showed reflex volume and maximal detrusor pressure were significant, and multivariate analysis showed maximal detrusor pressure is significantly associated with total ERPF.
• 3
  The study found a significant inverse relationship between renal function and maximal detrusor pressure, meaning an increase in maximal detrusor pressure is likely to result in decline of renal function.