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  4. Bibliometric analysis of stem cells for spinal cord injury: current status and emerging frontiers

Bibliometric analysis of stem cells for spinal cord injury: current status and emerging frontiers

Frontiers in Pharmacology, 2023 · DOI: 10.3389/fphar.2023.1235324 · Published: July 18, 2023

Spinal Cord InjuryPharmacologyRegenerative Medicine

Simple Explanation

This study uses a method called bibliometrics to look at research on stem cell therapy for spinal cord injuries. It analyzes published articles to see what the current research trends are, who the major contributors are, and what areas are likely to be important in the future. The study looks at things like which journals publish the most articles, which authors are most frequently cited, and which countries and institutions are most involved in this research area. By doing this, the study aims to give researchers a better understanding of the field. The study also uses keywords from the articles to identify the most popular research topics and predict where the field is headed. This can help researchers focus their efforts on the most promising areas of investigation.

Study Duration
2000 to 2022
Participants
Not specified
Evidence Level
Not specified

Key Findings

  • 1
    The study found that research on stem cell therapy for spinal cord injury has been increasing since 2000. Neural Regeneration Research was the journal with the most publications and the fastest cumulative publication growth.
  • 2
    Okano Hideyuki was the author with the highest number of publications and citations, Sun Yat-sen University was the institution with the highest number of publications, and China was the country with the highest number of publications.
  • 3
    Current research has focused on stem cell transplantation, neural regeneration, motor function recovery, exosomes, and tissue engineering. Future research directions are primarily concerned with the molecular mechanisms, safety, clinical trials, exosomes, scaffolds, hydrogels, and inflammatory responses.

Research Summary

This study provides a comprehensive analysis of the current research status and frontiers of stem cell therapy for spinal cord injury using bibliometric methods. It identifies key contributors, popular research areas, and potential future directions in the field. The findings indicate a growing interest in stem cell therapy for spinal cord injury, with specific journals, authors, institutions, and countries playing significant roles. However, the study also highlights the need for increased collaboration and communication within the field. The research suggests that future studies should focus on molecular mechanisms, safety, clinical trials, exosomes, scaffolds, hydrogels, and inflammatory responses to advance the clinical translation of stem cell therapy for spinal cord injury.

Practical Implications

Future Research Focus

Directs researchers to concentrate on molecular mechanisms, safety, clinical trials, and tissue engineering aspects of stem cell therapy.

Collaboration Enhancement

Encourages authors, institutions, and countries to strengthen their collaborative efforts to promote significant academic achievements.

Clinical Translation Strategies

Highlights the need for standardized transplantation strategies and improved clinical trial designs to enhance the effectiveness and safety of stem cell therapy.

Study Limitations

  • 1
    Exclusion of comments and non-English articles may have missed some popular research topics.
  • 2
    Inclusion of data only from the WoSCC database may overlook some research.
  • 3
    Merging different databases is not always the best option.

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