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  4. Assessment of nocturnal polyuria in patients with spinal cord injury at three different mobilization phases: A multicenter cross-sectional study

Assessment of nocturnal polyuria in patients with spinal cord injury at three different mobilization phases: A multicenter cross-sectional study

The Journal of Spinal Cord Medicine, 2024 · DOI: 10.1080/10790268.2021.2009674 · Published: January 1, 2024

Spinal Cord InjuryUrologyRehabilitation

Simple Explanation

This study investigates nocturnal polyuria (NP), a condition causing frequent nighttime urination, in patients with spinal cord injury (SCI). The researchers aimed to understand if the stage of rehabilitation (bedridden, wheelchair-bound, or using assistive devices) affects the prevalence of NP. The study also looked at whether the level and type of spinal cord injury influenced NP. They measured urine production during the night and compared it across different groups of patients. The findings suggest that NP is a common issue for SCI patients regardless of their rehabilitation phase or the specifics of their injury. The study suggests that two measurement methods, NPi and NUP, can both effectively determine the prevalence of NP in this patient group.

Study Duration
Not specified
Participants
40 patients with SCI
Evidence Level
Cross-sectional study

Key Findings

  • 1
    No significant difference was found in the presence of NP among SCI patients in different mobilization phases (bedridden, wheelchair, assistive device).
  • 2
    The study found no significant difference in NPi and NUP values between male and female patients, those with injury levels above or below T6, and those with complete or incomplete injuries.
  • 3
    NP was found to be a common problem in patients with SCI regardless of their mobilization phase, injury level and injury type.

Research Summary

This multicenter, cross-sectional study assessed the prevalence of nocturnal polyuria (NP) in 40 spinal cord injury (SCI) patients across three mobilization phases: confined to bed, wheelchair-bound, and standing with assistive devices. The results indicated that NP is a common issue for SCI patients, irrespective of their mobilization phase, injury level (above or below T6), or injury type (complete or incomplete). The study suggests that both nocturnal polyuria index (NPi) and nocturnal urine production (NUP) parameters can effectively determine the prevalence of NP in the SCI patient group.

Practical Implications

Clinical Assessment

Clinicians should be aware of the high prevalence of NP in SCI patients, regardless of their mobilization phase or injury characteristics.

Treatment Strategies

Consider behavioral modifications and potential therapies like compression stockings or desmopressin for managing NP in SCI patients.

CIC Management

The study suggests that an additional CIC at night may be beneficial for patients with SCI above T6 to reduce the risk of autonomic dysreflexia.

Study Limitations

  • 1
    Relatively low number of patients included in the study which might limit the generalizability of the results.
  • 2
    Lack of a gold standard method for the assessment of NP in SCI patients.
  • 3
    The study only included patients in the first 6 months after SCI and receiving rehabilitation for the first time.

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