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  4. Anxiety masquerading as autonomic dysreflexia

Anxiety masquerading as autonomic dysreflexia

The Journal of Spinal Cord Medicine, 2019 · DOI: 10.1080/10790268.2018.1518763 · Published: September 1, 2019

Spinal Cord InjuryMental HealthNeurology

Simple Explanation

Autonomic dysreflexia (AD) involves sudden high blood pressure in those with spinal cord injuries (SCI) at T6 or above. This report presents two SCI patients with high blood pressure due to anxiety, mimicking AD. Case 1: A 77-year-old male with C4 AIS D SCI experienced a rise in systolic blood pressure (SBP) from 138 to 170 mmHg without instrumentation. His SBP returned to normal when told urodynamics would be postponed. Case 2: A 57-year-old male with T12 AIS A SCI had elevated SBP during bladder filling. After stopping the filling and informing him the study was complete, his SBP decreased.

Study Duration
Not specified
Participants
Two individuals with spinal cord injuries
Evidence Level
Case Report

Key Findings

  • 1
    Anxiety can cause acute hypertension in SCI patients, mimicking autonomic dysreflexia (AD).
  • 2
    Episodic hypertension related to anxiety could explain some reports of AD in individuals with SCI below T6.
  • 3
    Increased catecholamines from anxiety might cause an accentuated blood pressure response in SCI patients due to alpha-1 adrenoreceptor hypersensitivity.

Research Summary

This report describes two cases where anxiety mimicked autonomic dysreflexia (AD) in patients with spinal cord injuries (SCI). The cases suggest that psychological state should be considered alongside traditional AD management when an SCI patient presents with hypertension. Anxiety-provoked hypertension may explain reports of AD in SCI patients with injuries below T6, especially during procedures like urodynamics.

Practical Implications

Differential Diagnosis

Clinicians should consider anxiety as a potential cause of hypertension in SCI patients, especially those with a history of anxiety or undergoing stressful procedures.

Individualized Treatment

Management of hypertension in SCI patients should include addressing potential anxiety triggers and providing appropriate anxiolytic interventions.

Re-evaluation of AD Cases

Reports of AD in patients with SCI below T6 should be re-evaluated to consider the potential role of anxiety-related hypertension.

Study Limitations

  • 1
    Small sample size (two cases)
  • 2
    Lack of objective measures of anxiety levels
  • 3
    Potential for other confounding factors contributing to hypertension

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