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  4. Acute dorsal genital nerve stimulation increases subjective arousal in women with and without spinal cord injury: a preliminary investigation

Acute dorsal genital nerve stimulation increases subjective arousal in women with and without spinal cord injury: a preliminary investigation

medRxiv preprint, 2023 · DOI: https://doi.org/10.1101/2023.04.24.23288935 · Published: December 23, 2023

Spinal Cord InjuryUrologyNeurology

Simple Explanation

This study investigates how stimulating certain nerves affects sexual arousal in women, including those with spinal cord injuries and those with female sexual dysfunction. The researchers used electrical stimulation on the dorsal genital nerve and tibial nerve to see if it could improve arousal. They found that stimulating the dorsal genital nerve increased subjective arousal in all women, suggesting it could be a potential treatment for female sexual dysfunction.

Study Duration
November 2020 and March 2022
Participants
9 women (3 with SCI, 3 with non-neurogenic FSD, and 3 without FSD or SCI)
Evidence Level
Not specified

Key Findings

  • 1
    Subjective arousal increased significantly from before to after stimulation in DGNS study sessions across all women.
  • 2
    TNS had no effect on subjective arousal.
  • 3
    Two participants with complete SCIs experienced genital sensations.

Research Summary

This study measured genital arousal in response to neuromodulation in women and found that acute DGNS, but not TNS, can increase subjective arousal. The effect of stimulation on genital arousal is inconclusive, but the study provides further support for DGNS as a treatment for female sexual dysfunction. Women with complete SCI experienced genital sensations in response to DGNS and TNS.

Practical Implications

Potential Treatment for FSD

DGNS could be a viable treatment option for women suffering from female sexual dysfunction, particularly those with challenges in physiological arousal.

Improved Sexual Function in SCI

Neuromodulation may offer a way to improve sexual function in women with spinal cord injuries, potentially restoring some level of sensation and arousal.

Further Research Needed

More extensive studies are needed to confirm these preliminary findings and to optimize the parameters of DGNS for maximum effectiveness.

Study Limitations

  • 1
    Small sample size (n = 3 per group)
  • 2
    Lack of audio-visual materials during the study procedure
  • 3
    Electrode placement for TNS or DGNS was not confirmed

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