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  4. A Nationwide Survey of Spinal Cord-Related Pain Syndrome in Japan: Clinical Characteristics and Treatment

A Nationwide Survey of Spinal Cord-Related Pain Syndrome in Japan: Clinical Characteristics and Treatment

Spine Surg Relat Res, 2019 · DOI: 10.22603/ssrr.2018-0096 · Published: January 1, 2019

Spinal Cord InjuryPain Management

Simple Explanation

This study focuses on chronic neuropathic pain (NeP) in patients with spinal cord damage, defining it as spinal cord-related pain syndrome. A nationwide survey was conducted in Japan to understand the prevalence, characteristics, and treatment of this syndrome. The goal was to gather information for planning effective control measures against spinal cord-related pain syndrome.

Study Duration
Not specified
Participants
3,401 patients
Evidence Level
Not specified

Key Findings

  • 1
    The most frequent underlying conditions were cervical spondylotic myelopathy (26.7%), spinal cord injury (17.4%), and ossification of the posterior longitudinal ligament (OPLL) of the cervical spine (14.1%).
  • 2
    62.5% reported at-level pain, among which 43.0% presented with allodynia, while 38.7% presented with below-level pain.
  • 3
    Anticonvulsants showed significantly higher effectiveness (31.1%) compared to other medications.

Research Summary

This nationwide survey investigated spinal cord-related pain syndrome in Japan, focusing on neuropathic pain associated with spinal cord damage. The study identified common underlying conditions, the prevalence of at-level and below-level pain, and the effectiveness of various treatments. The findings highlight the need for further classification of allodynia and symptom-based treatment approaches to improve pain management in these patients.

Practical Implications

Improved Diagnosis

Better understanding of the clinical characteristics of spinal cord-related pain syndrome can improve diagnosis.

Targeted Treatment

Tailoring treatment based on the level of pain (at-level vs. below-level) and the type of allodynia may enhance treatment effectiveness.

Medication Management

Considering the potential adverse effects and limited effectiveness of some medications, exploring alternative and multidisciplinary approaches is crucial.

Study Limitations

  • 1
    Low response rate to the survey
  • 2
    Potential selection bias in the study population
  • 3
    Possible inaccuracies in diagnosis due to the multiple centers involved

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