Browse the latest research summaries in the field of bioinformatics for spinal cord injury patients and caregivers.
Showing 331-334 of 334 results
Molecular & Cellular Proteomics, 2008 • May 14, 2008
This study demonstrates that aFGF is able to induce effective functional recovery after contusive spinal cord injury in rats. This was achieved through a single injection of aFGF. Proteomics analysis ...
KEY FINDING: aFGF treatment induces functional recovery of locomotion in contusive SCI rats, as demonstrated by improved BBB scores and CBS analysis.
BMC Biology, 2009 • January 13, 2009
Microarray analysis and 454 cDNA sequencing were used to identify nerve-dependent and independent gene expression changes during limb regeneration in the Mexican axolotl. The results show that limb re...
KEY FINDING: Considerable similarity was observed between NR and DL transcriptional programs at 5 and 14 days post amputation (dpa).
BMC Genomics, 2009 • January 13, 2009
This study provides the first DNA sequence data from a large salamander genome, revealing that genic regions, particularly introns, are significantly expanded compared to other vertebrates. The analys...
KEY FINDING: Axolotl introns are significantly longer (10x) than orthologous vertebrate introns, contributing substantially to the large genome size.
PLoS ONE, 2011 • April 22, 2011
This study uses lipidomic and peptidomic assays coupled to molecular mass spectrometry imaging to explore molecular changes after injury in the leech CNS. The study identifies proteins involved in cyt...
KEY FINDING: Increased levels of proteins thought to play important roles in early stages of neural development were observed in the regenerating adult leech CNS.