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  4. von Frey anesthesiometry to assess sensory impairment after acute spinal cord injury caused by thoracolumbar intervertebral disc extrusion in dogs

von Frey anesthesiometry to assess sensory impairment after acute spinal cord injury caused by thoracolumbar intervertebral disc extrusion in dogs

Vet J, 2016 · DOI: 10.1016/j.tvjl.2015.07.028 · Published: March 1, 2016

Spinal Cord InjuryNeurologyVeterinary Medicine

Simple Explanation

This study used an electric von Frey anesthesiometer (VFA) to measure sensory threshold (ST) in dogs with spinal cord injuries. The researchers compared ST values between normal dogs and dogs with acute thoracolumbar spinal cord injury (SCI). The study also looked at how ST values changed in SCI-affected dogs over a 30-day period following surgery.

Study Duration
1 Month
Participants
20 normal dogs and 29 dogs with acute thoracolumbar spinal cord injury
Evidence Level
Not specified

Key Findings

  • 1
    Pelvic limb ST values were significantly higher in SCI-affected dogs compared to normal dogs at days 3, 10, and 30 after surgery, indicating hypoalgesia.
  • 2
    A progressive decrease in pelvic limb ST values occurred in SCI-affected dogs over time, correlating inversely with locomotor scores.
  • 3
    Thoracic limb ST values did not differ significantly between SCI-affected dogs and normal dogs, but decreased slightly over time in both groups.

Research Summary

The study evaluated the feasibility of using a von Frey anesthesiometer (VFA) to measure sensory threshold (ST) in dogs with spinal cord injury (SCI). Results showed that pelvic limb ST values were significantly higher in SCI-affected dogs compared to normal dogs, and decreased over a 30-day period. The study highlights the need to control for clinical, environmental, and behavioral factors when using VFA to assess ST in dogs with SCI.

Practical Implications

Objective Sensory Assessment

VFA can be used to objectively measure sensory differences between normal and SCI-affected dogs.

Monitoring Recovery

Changes in ST values can be used to monitor sensory recovery in dogs after SCI.

Clinical Trial Considerations

Clinical and environmental factors must be considered to ensure reliable VFA results in clinical settings.

Study Limitations

  • 1
    Analgesic medications may influence ST values.
  • 2
    Environmental and behavioral factors can impact ST values.
  • 3
    Prolonged acclimation of subjects to the testing environment is not always feasible.

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