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  4. Use of Platelet Rich Plasma for the Treatment of Bicipital Tendinopathy in Spinal Cord Injury: A Pilot Study

Use of Platelet Rich Plasma for the Treatment of Bicipital Tendinopathy in Spinal Cord Injury: A Pilot Study

Top Spinal Cord Inj Rehabil, 2012 · DOI: 10.1310/sci1801-77 · Published: January 1, 2012

Spinal Cord InjuryRegenerative MedicineRehabilitation

Simple Explanation

This pilot study investigates the use of platelet-rich plasma (PRP) injections as a non-surgical treatment for shoulder tendinopathy in people with spinal cord injuries. The study focused on the biceps tendon and used ultrasound and physical exams to assess the effectiveness and safety of PRP injections. Initial findings suggest that PRP injections may be a safe and effective treatment for biceps tendinopathy in individuals with spinal cord injuries, warranting further investigation through larger randomized controlled trials.

Study Duration
8 weeks
Participants
8 spinal cord injured participants
Evidence Level
Pilot Study

Key Findings

  • 1
    The study demonstrated a significant change in the noninjected shoulder on USPRS score, in PESS score, and in the VAS-pain score.
  • 2
    Repeated measure general linear model analysis revealed statistical trends in the change of pain score measured via VAS at 5 time points for injected arm.
  • 3
    No adverse reactions were reported during the study period.

Research Summary

This pilot study explored the efficacy and safety of PRP injections for biceps tendinopathy in individuals with spinal cord injury. The study found significant improvements in pain and shoulder function based on USPRS, PESS, and VAS scores after PRP injection. The authors suggest further investigation is warranted, including a randomized controlled trial, based on the positive results observed.

Practical Implications

Potential Non-Operative Treatment

PRP injections could offer a non-surgical alternative for managing shoulder tendinopathy in individuals with SCI.

Improved Pain Management

The study suggests PRP injections can lead to significant pain reduction and improved shoulder function.

Further Research Needed

The findings warrant further investigation through randomized controlled trials to confirm the efficacy and safety of PRP treatment.

Study Limitations

  • 1
    Small sample size
  • 2
    Non-randomized design
  • 3
    Short follow-up period

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